H S Lee1, C Park1, S W Kim1, J W Song1, B K Chun2, T J Park3, J C Hong4, K D Lee1. 1. Department of Otolaryngology - Head and Neck Surgery,Kosin University College of Medicine,Busan,Korea. 2. Department of Pathology,Kosin University College of Medicine,Busan,Korea. 3. Department of Otolaryngology - Head and Neck Surgery,Maryknoll Medical Center,Busan,Korea. 4. Department of Otolaryngology - Head and Neck Surgery,Dong-A University College of Medicine,Busan,Korea.
Abstract
OBJECTIVE: This study evaluated whether primary tumour characteristics are associated with specific features of metastatic lymph nodes in papillary thyroid carcinoma patients. METHOD: A retrospective review of 411 patients with pathologically diagnosed cervical lymph node metastasis was conducted. RESULTS: A metastatic lymph node focus size of at least 2 mm was independently associated with a primary tumour size of at least 1 cm (hazard ratio 1.962) and with male sex (hazard ratio 1.947). A number of at least five lymph node metastases was independently associated with a primary tumour size of at least 1 cm (hazard ratio 2.863), extrathyroidal extension (hazard ratio 1.737) and male sex (hazard ratio 1.689). Extranodal extension was independently associated with a primary tumour size of at least 1 cm (hazard ratio 2.288), extrathyroidal extension (2.201) and male sex (hazard ratio 1.733). CONCLUSION: Primary papillary thyroid carcinoma characteristics are related to the pathological features of lymph node metastases.
OBJECTIVE: This study evaluated whether primary tumour characteristics are associated with specific features of metastatic lymph nodes in papillary thyroid carcinomapatients. METHOD: A retrospective review of 411 patients with pathologically diagnosed cervical lymph node metastasis was conducted. RESULTS: A metastatic lymph node focus size of at least 2 mm was independently associated with a primary tumour size of at least 1 cm (hazard ratio 1.962) and with male sex (hazard ratio 1.947). A number of at least five lymph node metastases was independently associated with a primary tumour size of at least 1 cm (hazard ratio 2.863), extrathyroidal extension (hazard ratio 1.737) and male sex (hazard ratio 1.689). Extranodal extension was independently associated with a primary tumour size of at least 1 cm (hazard ratio 2.288), extrathyroidal extension (2.201) and male sex (hazard ratio 1.733). CONCLUSION:Primary papillary thyroid carcinoma characteristics are related to the pathological features of lymph node metastases.
Authors: Ahmad M Eweida; Mahmoud F Sakr; Yasser Hamza; Mohamed R Khalil; Essam Gabr; Tarek Koraitim; Hatem F Al-Wagih; Waleed Abo-Elwafa; Tarek Ezzat Abdel-Aziz; Ahmed A Diab; Basma El-Sabaa; Aman S Nabawi Journal: Eur Arch Otorhinolaryngol Date: 2016-12-20 Impact factor: 2.503
Authors: Amjad O Aljohani; Reyan H Merdad; Anas I Alserif; Layan S Alhemayed; Noor Z Farsi; Thamer A Alsufyani; Haddad H Alkaf; Ameen Z Alherabi; Sherif K Abdelmonim; Mohammad A Alessa Journal: Ann Med Surg (Lond) Date: 2021-03-22