| Literature DB >> 26669094 |
Trevor N Clark, Katelyn T Ellsworth, Stephanie Jean, Duncan Webster, Duncan Webste, Gilles A Robichaud, John A Johnson, Christopher A Gray.
Abstract
An extract of an unidentified endophyte from the Canadian medicinal plant Heracleum maximum exhibited a unique metabolomic profile and significant antimycobacterial activity against Mycobacterium tuberculosis H37Ra. Bioassay guided fractionation of the extract led to the isolation of phomopsolide A (1) and 6(E)-phomopsolide A (2). This is the first report of antimycobacterial activity for 1 and 2.Entities:
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Year: 2015 PMID： 26669094
Source DB: PubMed Journal: Nat Prod Commun ISSN： 1555-9475 Impact factor: 0.986