Literature DB >> 26669092

Antimycobacterial Natural Products from Endophytes of the Medicinal Plant Aralia nudicaulis.

Haoxin Li, Brandon Doucet, Andrew J Flewelling, Stéphanie Jean, Duncan Webster, Gilles A Robichaud, John A Johnson, Christopher A Gray.   

Abstract

Antimycobacterial extracts of a Penicillium sp. (isolate HL4-159-41B) and a Coniothyrium sp. (isolate HL6-097-027B) isolated from the rhizomes of the Canadian medicinal plant Aralia nudicaulis were found to contain palitantin (1) and botrallin (2), craterellin C (3), mycosporulone (4), spiromassaritone (5), and massarigenin D (6) respectively. Bioassays against Mycobacterium tuberculosis H37Ra revealed that 1 - 4 possess moderate antimycobacterial activity.

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Year:  2015        PMID: 26669092

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN: 1555-9475            Impact factor:   0.986


  2 in total

Review 1.  Endophytic Penicillium species and their agricultural, biotechnological, and pharmaceutical applications.

Authors:  Rufin Marie Kouipou Toghueo; Fabrice Fekam Boyom
Journal:  3 Biotech       Date:  2020-02-08       Impact factor: 2.406

2.  American Civil War plant medicines inhibit growth, biofilm formation, and quorum sensing by multidrug-resistant bacteria.

Authors:  Micah Dettweiler; James T Lyles; Kate Nelson; Brandon Dale; Ryan M Reddinger; Daniel V Zurawski; Cassandra L Quave
Journal:  Sci Rep       Date:  2019-05-22       Impact factor: 4.379

  2 in total

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