PURPOSE: Skeletal muscle depletion is an important prognostic factor in patients with chronic obstructive pulmonary disease (COPD); a recent study demonstrated significant correlations between pectoralis muscle area on an axial CT image and COPD-related traits. The purpose of this study was to evaluate the relation between pectoralis muscle areas on CT scans and total body skeletal muscle mass (SMM) in healthy subjects. METHODS: For 434 subjects that underwent a low-dose chest CT and bioelectrical impedance analysis (BIA) during health screening from January to June of 2014, cross-sectional area of pectoralis muscles were measured in CT scans. Pearson's correlation and multiple linear regression analysis were used to assess the relationship between cross-sectional CT areas of pectoralis muscles and BIA-assessed SMMs. RESULTS: Mean age was 50 ± 10 years (78·8% were male). The mean cross-sectional area of pectoralis muscles was 24·1 cm2 ± 6·8. A moderate correlation was observed between pectoralis muscle area and BIA-based SMM (r = 0·665, P<0.001). Multivariable analysis showed CT determined pectoralis muscle area was significantly associated with BIA-assessed SMM after adjusting for gender, weight, height and age (β = 0·14 ± 0·02, P<0·001). CONCLUSION: Cross-sectional area of the pectoralis muscles on single axial CT images shows moderate correlation with total body SMM determined by BIA in healthy subjects.
PURPOSE: Skeletal muscle depletion is an important prognostic factor in patients with chronic obstructive pulmonary disease (COPD); a recent study demonstrated significant correlations between pectoralis muscle area on an axial CT image and COPD-related traits. The purpose of this study was to evaluate the relation between pectoralis muscle areas on CT scans and total body skeletal muscle mass (SMM) in healthy subjects. METHODS: For 434 subjects that underwent a low-dose chest CT and bioelectrical impedance analysis (BIA) during health screening from January to June of 2014, cross-sectional area of pectoralis muscles were measured in CT scans. Pearson's correlation and multiple linear regression analysis were used to assess the relationship between cross-sectional CT areas of pectoralis muscles and BIA-assessed SMMs. RESULTS: Mean age was 50 ± 10 years (78·8% were male). The mean cross-sectional area of pectoralis muscles was 24·1 cm2 ± 6·8. A moderate correlation was observed between pectoralis muscle area and BIA-based SMM (r = 0·665, P<0.001). Multivariable analysis showed CT determined pectoralis muscle area was significantly associated with BIA-assessed SMM after adjusting for gender, weight, height and age (β = 0·14 ± 0·02, P<0·001). CONCLUSION: Cross-sectional area of the pectoralis muscles on single axial CT images shows moderate correlation with total body SMM determined by BIA in healthy subjects.
Authors: Ariel Jaitovich; Malik M H S Khan; Ria Itty; Hau C Chieng; Camille L Dumas; Pallavi Nadendla; John P Fantauzzi; Recai M Yucel; Paul J Feustel; Marc A Judson Journal: Chest Date: 2018-10-28 Impact factor: 9.410
Authors: Eun Young Kim; Young Saing Kim; Inkeun Park; Hee Kyung Ahn; Eun Kyung Cho; Yu Mi Jeong; Jeong Ho Kim Journal: Support Care Cancer Date: 2016-06-30 Impact factor: 3.603
Authors: Balázs Poros; Andrea Sabine Becker-Pennrich; Bastian Sabel; Hans Joachim Stemmler; Dietmar Wassilowsky; Thomas Weig; Ludwig Christian Hinske; Bernhard Zwissler; Jens Ricke; Dominik J Hoechter Journal: Obes Med Date: 2021-07-03