The neuroscience of adolescent decision-making.

Adolescence is a phase of lifespan associated with greater independence, and thus greater demands to make self-guided decisions in the face of risks, uncertainty, and varying proximal and distal outcomes. A new wave of developmental research takes a neuroeconomic approach to specify what decision processes are changing during adolescence, along what trajectory they are changing, and what neurodevelopmental processes support these changes. Evidence is mounting to suggest that multiple decision processes are tuned differently in adolescents and adults including reward reactivity, uncertainty-tolerance, delay discounting, and experiential assessments of value and risk. Unique interactions between prefrontal cortical, striatal, and salience processing systems during adolescence both constrain and amplify various component processes of mature decision-making.