Literature DB >> 26663821

Viral chemistry: the chemical functionalization of viral architectures to create new technology.

Zhuo Chen1, Na Li1, Shaobo Li1, Madushani Dharmarwardana1, Anna Schlimme1, Jeremiah J Gassensmith1.   

Abstract

The modification of viruses using chemical conjugation techniques has brought the distant worlds of virology right into the center of nanotechnology. Viruses are naturally resilient biomolecules and this makes them exceptional templates for the creation of higher order polymers and as scaffolds for biological imaging and targeted drug delivery. In this review, we highlight progress in utilizing chemical strategies to interface viruses with synthetic polymers, to create bright bionanoparticles using synthetic fluorescent dyes, and how orthogonal chemical transformations allow for targeted drug delivery. WIREs Nanomed Nanobiotechnol 2016, 8:512-534. doi: 10.1002/wnan.1379 For further resources related to this article, please visit the WIREs website.
© 2015 Wiley Periodicals, Inc.

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Year:  2015        PMID： 26663821     DOI： 10.1002/wnan.1379

Source DB:  PubMed          Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol        ISSN： 1939-0041


  7 in total

1.  Making Conjugation-induced Fluorescent PEGylated Virus-like Particles by Dibromomaleimide-disulfide Chemistry.

Authors:  Zhuo Chen; Stacey T Detvo; Elizabeth Pham; Jeremiah J Gassensmith
Journal:  J Vis Exp       Date:  2018-05-27       Impact factor: 1.355

2.  Polymer Structure and Conformation Alter the Antigenicity of Virus-like Particle-Polymer Conjugates.

Authors:  Parker W Lee; Sergey A Isarov; Jaqueline D Wallat; Sudheer K Molugu; Sourabh Shukla; Jessie E P Sun; Jun Zhang; Yi Zheng; Melissa Lucius Dougherty; Dominik Konkolewicz; Phoebe L Stewart; Nicole F Steinmetz; Michael J A Hore; Jonathan K Pokorski
Journal:  J Am Chem Soc       Date:  2017-01-25       Impact factor: 15.419

3.  One-Step Supramolecular Multifunctional Coating on Plant Virus Nanoparticles for Bioimaging and Therapeutic Applications.

Authors:  Zhuohong Wu; Jiajing Zhou; Christian Isalomboto Nkanga; Zhicheng Jin; Tengyu He; Raina M Borum; Wonjun Yim; Jingcheng Zhou; Yong Cheng; Ming Xu; Nicole F Steinmetz; Jesse V Jokerst
Journal:  ACS Appl Mater Interfaces       Date:  2022-03-08       Impact factor: 10.383

4.  Equilibrium mechanisms of self-limiting assembly.

Authors:  Michael F Hagan; Gregory M Grason
Journal:  Rev Mod Phys       Date:  2021-06-11       Impact factor: 50.485

5.  Nitroxyl Modified Tobacco Mosaic Virus as a Metal-Free High-Relaxivity MRI and EPR Active Superoxide Sensor.

Authors:  Madushani Dharmarwardana; André F Martins; Zhuo Chen; Philip M Palacios; Chance M Nowak; Raymond P Welch; Shaobo Li; Michael A Luzuriaga; Leonidas Bleris; Brad S Pierce; A Dean Sherry; Jeremiah J Gassensmith
Journal:  Mol Pharm       Date:  2018-05-29       Impact factor: 4.939

6.  Defects and Chirality in the Nanoparticle-Directed Assembly of Spherocylindrical Shells of Virus Coat Proteins.

Authors:  Cheng Zeng; Guillermo Rodriguez Lázaro; Irina B Tsvetkova; Michael F Hagan; Bogdan Dragnea
Journal:  ACS Nano       Date:  2018-04-25       Impact factor: 15.881

7.  Multifunctionalized biocatalytic P22 nanoreactor for combinatory treatment of ER+ breast cancer.

Authors:  Kanchan Chauhan; Juan M Hernandez-Meza; Ana G Rodríguez-Hernández; Karla Juarez-Moreno; Prakhar Sengar; Rafael Vazquez-Duhalt
Journal:  J Nanobiotechnology       Date:  2018-02-20       Impact factor: 10.435
  7 in total

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