Literature DB >> 26662802

Circulating epigenetic biomarkers in melanoma.

Yu Xin1, Zheng Li2, Matthew T V Chan3, William Ka Kei Wu3,4.   

Abstract

Recent researches have shed new light on the importance of epigenetic alterations, including promoter hypermethylation and microRNA dysregulation, in the initiation and progression of melanoma. The clinical utilization of circulating epigenetic markers in melanoma has also been investigated. In this review, we explored the literature and summarized the latest progress in the discovery of circulating epigenetic markers, namely methylated DNA and microRNAs, for non-invasive diagnosis of melanoma, as well as their measurability and predictability. We also discussed the utility of these epigenetic markers as novel prognostic and predictive markers and their association with melanoma clinical phenotypes, including recurrence and patients' survival. Large-cohort validations are warranted to maximize the clinical utilization of these markers.

Entities:  

Keywords:  Circulating biomarkers; Epigenetic; Melanoma; miRNA

Mesh：

Substances：

Year:  2015        PMID： 26662802     DOI： 10.1007/s13277-015-4599-0

Source DB:  PubMed          Journal:  Tumour Biol        ISSN： 1010-4283


  72 in total

Review 1.  Epigenetic biomarkers in lung cancer.

Authors:  Triantafillos Liloglou; Naiara G Bediaga; Benjamin R B Brown; John K Field; Michael P A Davies
Journal:  Cancer Lett       Date:  2012-04-27       Impact factor: 8.679

2.  Epigenetic regulation of microRNA-375 and its role in melanoma development in humans.

Authors:  Joseph Mazar; Dan DeBlasio; Subramaniam S Govindarajan; Shaojie Zhang; Ranjan J Perera
Journal:  FEBS Lett       Date:  2011-06-26       Impact factor: 4.124

Review 3.  Histone Deacetylase Inhibitors for Cutaneous T-Cell Lymphoma.

Authors:  Madeleine Duvic
Journal:  Dermatol Clin       Date:  2015-08-29       Impact factor: 3.478

4.  Skin self-examination behaviors among individuals diagnosed with melanoma.

Authors:  Elliot J Coups; Sharon L Manne; Jerod L Stapleton; Kristina L Tatum; James S Goydos
Journal:  Melanoma Res       Date:  2016-02       Impact factor: 3.599

Review 5.  MicroRNAs predict and modulate responses to chemotherapy in colorectal cancer.

Authors:  Xin Yu; Zheng Li; Jun Yu; Matthew T V Chan; William K K Wu
Journal:  Cell Prolif       Date:  2015-07-22       Impact factor: 6.831

Review 6.  MicroRNA dysregulation in rhabdomyosarcoma: a new player enters the game.

Authors:  Zheng Li; Xin Yu; Jianxiong Shen; Yang Liu; Matthew T V Chan; William K K Wu
Journal:  Cell Prolif       Date:  2015-07-23       Impact factor: 6.831

7.  Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients.

Authors:  Dave S B Hoon; Mia Spugnardi; Christine Kuo; Sharon K Huang; Donald L Morton; Bret Taback
Journal:  Oncogene       Date:  2004-05-13       Impact factor: 9.867

Review 8.  MicroRNA dysregulation in uveal melanoma: a new player enters the game.

Authors:  Zheng Li; Xin Yu; Jianxiong Shen; Yang Jiang
Journal:  Oncotarget       Date:  2015-03-10

Review 9.  The role of microRNAs expression in laryngeal cancer.

Authors:  Xin Yu; Zheng Li
Journal:  Oncotarget       Date:  2015-09-15

10.  Methylated tissue factor pathway inhibitor 2 (TFPI2) DNA in serum is a biomarker of metastatic melanoma.

Authors:  Cristiana Lo Nigro; Hexiao Wang; Angela McHugh; Laura Lattanzio; Rubeta Matin; Catherine Harwood; Nelofer Syed; Eleftheria Hatzimichael; Evangelos Briasoulis; Marco Merlano; Alan Evans; Alastair Thompson; Irene Leigh; Colin Fleming; Gareth J Inman; Charlotte Proby; Tim Crook
Journal:  J Invest Dermatol       Date:  2013-02-14       Impact factor: 8.551
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  4 in total

1.  The long non-coding RNA UPAT promotes gastric cancer cell progression via UHRF1.

Authors:  Chaoyong Liu; Minghua Ai; Yan Zhang; Jie Li; Chao Xu
Journal:  Genes Genomics       Date:  2022-03-16       Impact factor: 2.164

Review 2.  Long non-coding RNAs in melanoma.

Authors:  Xin Yu; Heyi Zheng; Gary Tse; Matthew Tv Chan; William Kk Wu
Journal:  Cell Prolif       Date:  2018-03-26       Impact factor: 6.831

3.  Extracellular microvesicle microRNAs as predictive biomarkers for targeted therapy in metastastic cutaneous malignant melanoma.

Authors:  Fernanda Costa Svedman; Warangkana Lohcharoenkal; Matteo Bottai; Suzanne Egyhazi Brage; Enikö Sonkoly; Johan Hansson; Andor Pivarcsi; Hanna Eriksson
Journal:  PLoS One       Date:  2018-11-06       Impact factor: 3.240

4.  MicroRNA-204-3p modulates epithelial-mesenchymal transition by targeting paired box gene 2 in human melanoma A-375 cells.

Authors:  Jun Song; Xinyan Chen; Liping Zhang; Dandan Song; Huizi Xiong
Journal:  Transl Cancer Res       Date:  2019-09       Impact factor: 1.241
  4 in total

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