Literature DB >> 26662290

Abscopal Effects and Yttrium-90 Radioembolization.

Anish Ghodadra1, Sumantha Bhatt1, Juan C Camacho2, Hyun S Kim3,4,5.   

Abstract

We present the case of an 80-year-old male with squamous cell carcinoma with bilobar hepatic metastases who underwent targeted Yttrium-90 radioembolization of the right hepatic lobe lesion. Subsequently, there was complete regression of the nontargeted, left hepatic lobe lesion. This may represent the first ever reported abscopal effect in radioembolization. The abscopal effect refers to the phenomenon of tumor response in nontargeted sites after targeted radiotherapy. In this article, we briefly review the immune-mediated mechanisms responsible for the abscopal effect.

Entities:  

Keywords:  Hepatic; Interventional oncology; Liver; Neoplasm; Radioembolization; Tumor

Mesh：

Substances：

Year:  2015        PMID： 26662290     DOI： 10.1007/s00270-015-1259-0

Source DB:  PubMed          Journal:  Cardiovasc Intervent Radiol        ISSN： 0174-1551            Impact factor:   2.740


  9 in total

Review 1.  Locoregional Therapy, Immunotherapy and the Combination in Hepatocellular Carcinoma: Future Directions.

Authors:  Meaghan S Dendy; Johannes M Ludwig; Stacey M Stein; Hyun S Kim
Journal:  Liver Cancer       Date:  2019-01-16       Impact factor: 11.740

Review 2.  Current locoregional therapies and treatment strategies in hepatocellular carcinoma.

Authors:  L Cardarelli-Leite; A Hadjivassiliou; D Klass; J Chung; S G F Ho; H J Lim; P T W Kim; A Mujoomdar; D M Liu
Journal:  Curr Oncol       Date:  2020-11-01       Impact factor: 3.677

Review 3.  Immunotherapy and the Interventional Oncologist: Challenges and Opportunities-A Society of Interventional Oncology White Paper.

Authors:  Joseph P Erinjeri; Gabriel C Fine; Gosse J Adema; Muneeb Ahmed; Julius Chapiro; Martijn den Brok; Rafael Duran; Stephen J Hunt; D Thor Johnson; Jens Ricke; Daniel Y Sze; Beau Bosko Toskich; Bradford J Wood; David Woodrum; S Nahum Goldberg
Journal:  Radiology       Date:  2019-04-23       Impact factor: 11.105

4.  Abscopal Effect after Radioembolization for Metastatic Breast Cancer in the Setting of Immunotherapy.

Authors:  Amy R Deipolyi; Jacqueline F Bromberg; Joseph P Erinjeri; Stephen B Solomon; Lynn A Brody; Christopher C Riedl
Journal:  J Vasc Interv Radiol       Date:  2018-03       Impact factor: 3.682

Review 5.  Immuno-thermal ablations - boosting the anticancer immune response.

Authors:  Ryan Slovak; Johannes M Ludwig; Scott N Gettinger; Roy S Herbst; Hyun S Kim
Journal:  J Immunother Cancer       Date:  2017-10-17       Impact factor: 13.751

6.  Interventional oncology update.

Authors:  Alex Newbury; Chantal Ferguson; Daniel Alvarez Valero; Roberto Kutcher-Diaz; Lacey McIntosh; Ara Karamanian; Aaron Harman
Journal:  Eur J Radiol Open       Date:  2022-06-20

7.  Concomitant Radioembolization and Immune Checkpoint Inhibition in Metastatic Renal Cell Carcinoma.

Authors:  Jacob J Adashek; Meghan Salgia; Nazli Dizman; Jonathan Kessler; Sumanta K Pal
Journal:  Case Rep Oncol       Date:  2018-05-17

Review 8.  Immune Checkpoint Inhibitors as Monotherapy or Within a Combinatorial Strategy in Advanced Hepatocellular Carcinoma.

Authors:  Michela Guardascione; Giuseppe Toffoli
Journal:  Int J Mol Sci       Date:  2020-08-31       Impact factor: 5.923

9.  Intra-hepatic Abscopal Effect Following Radioembolization of Hepatic Metastases.

Authors:  Maciej Powerski; Ralph Drewes; Jazan Omari; Borna Relja; Alexey Surov; Maciej Pech
Journal:  Cardiovasc Intervent Radiol       Date:  2020-08-17       Impact factor: 2.740
  9 in total

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