Literature DB >> 26661283

Subacute, tetracycline-responsive, granulomatous osteomyelitis in an adult man, consistent with Q fever infection.

Cornelia Bayard1, Alexis Dumoulin2, Kristian Ikenberg3, Huldrych F Günthard1.   

Abstract

Osteomyelitis due to Coxiella burnetii infection is a rare condition in adults. We report the case of a healthy young man presenting with subacute osteomyelitis of the left cheek bone, evolving gradually after an episode of acute febrile illness. Histological evaluation confirmed subacute granulomatous inflammation. Despite antibody titres not reaching the standard cut-off for chronic Q fever (phase I IgG 1/160, phase II IgG 1/2560), osteomyelitis was radiologically and histologically confirmed. A 6-month course of doxycycline/hydroxychloroquine brought clinical and radiological cure while various conventional antibiotic treatments had failed to improve the clinical condition. Currently, at 6-month follow-up, no relapse has occurred and antibody titres have declined. A shorter course of doxycycline/hydroxychloroquine than that used for chronic Q fever osteomyelitis may be sufficient to treat subacute Q fever osteomyelitis in some cases. 2015 BMJ Publishing Group Ltd.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 26661283      PMCID： PMC4680291          DOI： 10.1136/bcr-2015-212426

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  14 in total

1.  Interlaboratory evaluation of different extraction and real-time PCR methods for detection of Coxiella burnetii DNA in serum.

Authors:  Jeroen J H C Tilburg; Willem J G Melchers; Annika M Pettersson; John W A Rossen; Mirjam H A Hermans; Erik J van Hannen; Marrigje H Nabuurs-Franssen; Maaike C de Vries; Alphons M Horrevorts; Corné H W Klaassen
Journal:  J Clin Microbiol       Date:  2010-09-08       Impact factor: 5.948

Review 2.  Q fever osteomyelitis: a case report and literature review.

Authors:  Vicky Merhej; Pierre Tattevin; Matthieu Revest; Bastien Le Touvet; Didier Raoult
Journal:  Comp Immunol Microbiol Infect Dis       Date:  2012-01-27       Impact factor: 2.268

3.  Chronic Q fever: expert opinion versus literature analysis and consensus.

Authors:  Didier Raoult
Journal:  J Infect       Date:  2012-04-23       Impact factor: 6.072

Review 4.  Q fever: still more queries than answers.

Authors:  Corine E Delsing; Adilia Warris; Chantal P Bleeker-Rovers
Journal:  Adv Exp Med Biol       Date:  2011       Impact factor: 2.622

5.  A case of multifocal chronic Q fever osteomyelitis.

Authors:  E Acquacalda; H Montaudie; C Laffont; P-E Fournier; C Pulcini
Journal:  Infection       Date:  2011-01-11       Impact factor: 3.553

6.  Persistence of DNA in a cured patient and positive culture in cases with low antibody levels bring into question diagnosis of Q fever endocarditis.

Authors:  Sophie Edouard; Matthieu Million; Hubert Lepidi; Jean-Marc Rolain; Pierre-Edouard Fournier; Bernard La Scola; Dominique Grisoli; Didier Raoult
Journal:  J Clin Microbiol       Date:  2013-07-12       Impact factor: 5.948

Review 7.  Chronic Q fever: review of the literature and a proposal of new diagnostic criteria.

Authors:  M C A Wegdam-Blans; L M Kampschreur; C E Delsing; C P Bleeker-Rovers; T Sprong; M E E van Kasteren; D W Notermans; N H M Renders; H A Bijlmer; P J Lestrade; M P G Koopmans; M H Nabuurs-Franssen; J J Oosterheert
Journal:  J Infect       Date:  2011-12-23       Impact factor: 6.072

8.  Long-term outcome of Q fever endocarditis: a 26-year personal survey.

Authors:  Matthieu Million; Franck Thuny; Hervé Richet; Didier Raoult
Journal:  Lancet Infect Dis       Date:  2010-07-14       Impact factor: 25.071

Review 9.  Three cases of Q fever osteomyelitis in children and a review of the literature.

Authors:  Clare Nourse; Anthony Allworth; Andrew Jones; Robert Horvath; Joe McCormack; Jeremy Bartlett; David Hayes; Jennifer M Robson
Journal:  Clin Infect Dis       Date:  2004-09-13       Impact factor: 9.079

10.  Therapeutic impact of the correlation of doxycycline serum concentrations and the decline of phase I antibodies in Q fever endocarditis.

Authors:  Audrey Lecaillet; Marie-Noëlle Mallet; Didier Raoult; Jean-Marc Rolain
Journal:  J Antimicrob Chemother       Date:  2009-02-13       Impact factor: 5.790
View more
  1 in total

Review 1.  From Q Fever to Coxiella burnetii Infection: a Paradigm Change.

Authors:  Carole Eldin; Cléa Mélenotte; Oleg Mediannikov; Eric Ghigo; Matthieu Million; Sophie Edouard; Jean-Louis Mege; Max Maurin; Didier Raoult
Journal:  Clin Microbiol Rev       Date:  2017-01       Impact factor: 26.132
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.