Sarcoidosis.

Sarcoidosis is characterized by noncaseating granuloma that can occur in any organ of the body. The lymph nodes, lungs, skin, liver, spleen, phalangeal bones, parotid glands, and eyes are the most common sites of involvement. Although sarcoidosis rarely causes death, its course is highly variable, and its treatment can be challenging to the clinician. This article presents an updated review of the clinical manifestations of sarcoidosis as well as discussions of the diagnostic evaluation and treatment of this idiopathic disease.