| Literature DB >> 26659332 |
Raghunath Reddy Anugu1, Prathama S Mainkar, Balasubramanian Sridhar, Srivari Chandrasekhar.
Abstract
(±)-Asenapine, sold in the market as Saphris/Sycrest for the treatment of bipolar disorders, is synthesized in an optically pure form involving an Ireland-Claisen rearrangement as the key step. This approach allows access to all diastereomers.Entities:
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Year: 2015 PMID： 26659332 DOI： 10.1039/c5ob02047f
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876