Literature DB >> 26659241

Laparoscopic splenic vessels ligation as a treatment of hypersplenism and thrombocytopenia in children.

Jin-Shan Zhang1, Long Li2, Qi Li1, Wei Cheng3,4.   

Abstract

BACKGROUND: Splenectomy and partial splenic embolization as the surgical approach in the treatment of hypersplenism and thrombocytopenia have been reported. However, there are still some disadvantages in the application of these techniques. In this article, we propose a new technique for the treatment of hypersplenism and thrombocytopenia in children and report our preliminary experience.
METHODS: From Aug 2014 to Dec 2014, four children with hypersplenism and three children with idiopathic thrombocytopenic purpura were treated in our hospital. Laparoscopic splenic vessels ligation was performed in all patients. The gastric wall was suspended to expose the pancreatic tail and spleen, and the splenic artery was ligated at the superior border of the pancreas. The splenic venous branches were dissected and ligated at the splenic hilum using the Hem-o-lok.
RESULTS: The laparoscopic splenic vessels ligation was successfully performed in all patients. The average operative time was 126 min (range 120-150 min). No patient required transfusion, and the length of hospital stay varied from 4 to 11 days (mean 6.6 days). The patients were followed up for 6-10 months (mean 8.5 months). The complete blood counts were within normal range. The size of spleen decreased postoperatively. The partial splenic infarction and the reduction in splenic blood flow were confirmed in all patients by postoperative ultrasound and CT.
CONCLUSIONS: The laparoscopic splenic vessels ligation is a feasible option for treating hypersplenism and thrombocytopenia in children.

Entities:  

Keywords:  Children; Hypersplenism; Laparoscopy; Splenic vessels ligation; Thrombocytopenia

Mesh:

Year:  2015        PMID: 26659241     DOI: 10.1007/s00464-015-4698-4

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  18 in total

1.  The effects of splenic artery ligation in an experimental model of secondary hypersplenism.

Authors:  M Sahin; S Tekin; F Aksoy; H Vatansev; M Seker; M C Avunduk; A Kartal
Journal:  J R Coll Surg Edinb       Date:  2000-06

2.  Partial splenic embolization in the treatment of hypersplenism.

Authors:  D G Spigos; O Jonasson; M Mozes; V Capek
Journal:  AJR Am J Roentgenol       Date:  1979-05       Impact factor: 3.959

3.  Quantitative determination of splenic red blood cell destruction in patients with splenomegaly.

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Journal:  Scand J Haematol       Date:  1975-05

4.  [Organ-preserving method in the surgical treatment of the spleen injuries].

Authors:  A I Khripun; A N Alimov; A V Salikov; A D Priamikov; V A Alimov; A A Sukiasian; T V Popov; O M Urvantseva
Journal:  Khirurgiia (Mosk)       Date:  2014

5.  Partial splenic embolization as an alternative to splenectomy in hypersplenism--single center experience in 16 years.

Authors:  G Alzen; J Basedow; M Luedemann; L D Berthold; K-P Zimmer
Journal:  Klin Padiatr       Date:  2010-09-22       Impact factor: 1.349

Review 6.  Splenomegaly, hypersplenism and coagulation abnormalities in liver disease.

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Journal:  Baillieres Best Pract Res Clin Gastroenterol       Date:  2000-12

7.  Partial splenic embolization versus splenectomy for the management of hypersplenism in cirrhotic patients.

Authors:  Mahmoud A Amin; Mohamed M el-Gendy; Ibrahim E Dawoud; Ashraf Shoma; Ahmed M Negm; Talal A Amer
Journal:  World J Surg       Date:  2009-08       Impact factor: 3.352

8.  Combined treatment of hepatocellular carcinoma with partial splenic embolization and transcatheter hepatic arterial chemoembolization.

Authors:  Jin-Hua Huang; Fei Gao; Yang-Kui Gu; Wen-Quan Li; Lian-Wei Lu
Journal:  World J Gastroenterol       Date:  2007-12-28       Impact factor: 5.742

9.  Partial splenic embolization.

Authors:  Hiroshi Yoshida; Yasuhiro Mamada; Nobuhiko Taniai; Takashi Tajiri
Journal:  Hepatol Res       Date:  2007-11-23       Impact factor: 4.288

Review 10.  Clinical application of partial splenic embolization.

Authors:  Yong-Song Guan; Ying Hu
Journal:  ScientificWorldJournal       Date:  2014-11-03
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  2 in total

1.  Laparoscopic ligation of splenic vessels for the treatment of hereditary spherocytosis in children.

Authors:  Jin-Shan Zhang; Long Li
Journal:  Pediatr Surg Int       Date:  2020-01-25       Impact factor: 1.827

2.  Laparoscopic distal splenoadrenal shunt for the treatment of portal hypertension in children with congenital hepatic fibrosis: A case report.

Authors:  Jin-Shan Zhang; Wei Cheng; Long Li
Journal:  Medicine (Baltimore)       Date:  2017-01       Impact factor: 1.889

  2 in total

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