Literature DB >> 26658952

Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths.

Takehiko Ishii1, Kanjiro Miyata2, Yasutaka Anraku3, Mitsuru Naito2, Yu Yi1, Takao Jinbo3, Seiji Takae3, Yu Fukusato1, Mao Hori1, Kensuke Osada1, Kazunori Kataoka4.   

Abstract

Monodispersed gold nanoparticles (AuNPs) were simultaneously decorated with lactosylated and non-modified shorter poly(ethylene glycol)s (PEGs) to enhance their target recognition. The decoration with sufficiently shorter PEGs dramatically enhanced the multivalent binding ability of lactosylated AuNPs to the lectin-fixed surface, possibly due to the enhanced mobility of the ligands via the spacer effect generated by the shorter PEG chains.

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Year:  2016        PMID: 26658952     DOI: 10.1039/c5cc06661a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  4 in total

1.  Atomic-level characterization and cilostazol affinity of poly(lactic acid) nanoparticles conjugated with differentially charged hydrophilic molecules.

Authors:  María Francisca Matus; Martín Ludueña; Cristian Vilos; Iván Palomo; Marcelo M Mariscal
Journal:  Beilstein J Nanotechnol       Date:  2018-05-02       Impact factor: 3.649

2.  Protein Removal from Hydrogels through Repetitive Surface Degradation.

Authors:  Tatsuki Kamiya; Syuuhei Komatsu; Akihiko Kikuchi
Journal:  ACS Appl Bio Mater       Date:  2021-11-19

3.  Quantifying the effect of PEG architecture on nanoparticle ligand availability using DNA-PAINT.

Authors:  Teodora Andrian; Silvia Pujals; Lorenzo Albertazzi
Journal:  Nanoscale Adv       Date:  2021-11-01

4.  Cancer Nanomedicines Stabilized by π-π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations.

Authors:  Hangxiang Wang; Jianmei Chen; Chang Xu; Linlin Shi; Munire Tayier; Jiahui Zhou; Jun Zhang; Jiaping Wu; Zhijian Ye; Tao Fang; Weidong Han
Journal:  Theranostics       Date:  2017-08-23       Impact factor: 11.556

  4 in total

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