Literature DB >> 26658626

Vaccine Failures in Patients Properly Vaccinated with 13-Valent Pneumococcal Conjugate Vaccine in Catalonia, a Region with Low Vaccination Coverage.

Fernando Moraga-Llop1, Juan-Jose Garcia-Garcia, Alvaro Díaz-Conradi, Pilar Ciruela, Johanna Martínez-Osorio, Sebastià González-Peris, Sergi Hernández, Mariona Fernández de Sevilla, Sonia Uriona, Conchita Izquierdo, Laura Selva, Magda Campins, Gemma Codina, Joan Batalla, Cristina Esteva, Àngela Domínguez, Carmen Muñoz-Almagro.   

Abstract

Vaccine failures occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in 3 pediatric hospitals in Barcelona (2012-2013) are described. PCV13 vaccine failure was defined as the occurrence of an invasive pneumococcal infection in children properly vaccinated by PCV13. Among 84 patients with invasive pneumococcal infection, 32 had received at least one dose of PCV13. Seventeen of them had invasive pneumococcal infection produced by a PCV13 serotype. Among those, 9 patients were considered to have a PCV13 vaccine failure. Serotype 3 was isolated in 6 patients, serotype 19A in 2 and serotype 6B in 1.

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Year:  2016        PMID: 26658626     DOI: 10.1097/INF.0000000000001041

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN: 0891-3668            Impact factor:   2.129


  21 in total

1.  Occult bacteremia etiology following the introduction of 13-valent pneumococcal conjugate vaccine: a multicenter study in Spain.

Authors:  Susanna Hernández-Bou; Borja Gómez; Santiago Mintegi; Juan J García-García
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2018-05-07       Impact factor: 3.267

2.  Other age groups than children need to be considered as carriers of Streptococcal pneumoniae serotypes.

Authors:  Hans-Christian Slotved
Journal:  Hum Vaccin Immunother       Date:  2016-06-20       Impact factor: 3.452

Review 3.  Prevention of Invasive Pneumococcal Disease: Problems Emerged After Some Years of the 13-Valent Pneumococcal Conjugate Vaccine Use.

Authors:  Nicola Principi; Giuseppe Di Cara; Ilaria Bizzarri; Chiara Isidori; Paola Borgia; Costanza Mignini; Marco Saponara; Alberto Argentiero; Susanna Esposito
Journal:  Curr Infect Dis Rep       Date:  2018-01-24       Impact factor: 3.725

4.  Routine infant vaccination of pneumococcal conjugate vaccines has decreased pneumonia across all age groups in Northern Spain.

Authors:  I Rivero-Calle; J Pardo Seco; P F Raguindin; F Alvez; J Gómez-Rial; A Salas; J Martinón Sanchez; F Martinón-Torres
Journal:  Hum Vaccin Immunother       Date:  2019-12-18       Impact factor: 3.452

5.  Vaccine failures in pediatric cases caused by streptococcus pneumoniae serotype 19A.

Authors:  Aslinur Ozkaya-Parlakay; Meltem Polat; Tugba Bedir Demirdag; Belgin Gulhan; Saliha Kanik-Yuksek; Selin Nar-Otgun
Journal:  Hum Vaccin Immunother       Date:  2020-07-23       Impact factor: 3.452

6.  Prevnar-13 vaccine failure in a mouse model for vitamin A deficiency.

Authors:  Rhiannon R Penkert; Amy Iverson; Jason W Rosch; Julia L Hurwitz
Journal:  Vaccine       Date:  2017-10-09       Impact factor: 3.641

7.  A Capsular Polysaccharide-Specific Antibody Alters Streptococcus pneumoniae Gene Expression during Nasopharyngeal Colonization of Mice.

Authors:  Christopher R Doyle; Jee-Young Moon; Johanna P Daily; Tao Wang; Liise-Anne Pirofski
Journal:  Infect Immun       Date:  2018-06-21       Impact factor: 3.441

8.  The 13-valent pneumococcal conjugate vaccine (PCV13) does not appear to provide much protection on combined invasive disease due to the six PCV13 non-PCV7 serotypes 1, 3, 5, 6A, 7F, and 19A in Kuwait during 2010-2019.

Authors:  Eiman Mokaddas; Shabeera Syed; M John Albert
Journal:  Hum Vaccin Immunother       Date:  2021-08-26       Impact factor: 4.526

9.  Invasive pneumococcal disease rates linked to meteorological factors and respiratory virus circulation (Catalonia, 2006-2012).

Authors:  Pilar Ciruela; Sonia Broner; Conchita Izquierdo; Sergi Hernández; Carmen Muñoz-Almagro; Roman Pallarés; Mireia Jané; Angela Domínguez
Journal:  BMC Public Health       Date:  2016-05-13       Impact factor: 3.295

10.  Serotypes and Clonal Diversity of Streptococcus pneumoniae Causing Invasive Disease in the Era of PCV13 in Catalonia, Spain.

Authors:  Eva Del Amo; Cristina Esteva; Susanna Hernandez-Bou; Carmen Galles; Marian Navarro; Goretti Sauca; Alvaro Diaz; Paula Gassiot; Carmina Marti; Nieves Larrosa; Pilar Ciruela; Mireia Jane; Raquel Sá-Leão; Carmen Muñoz-Almagro
Journal:  PLoS One       Date:  2016-03-08       Impact factor: 3.240

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