Literature DB >> 26657959

Heteroreceptor Complexes and their Allosteric Receptor-Receptor Interactions as a Novel Biological Principle for Integration of Communication in the CNS: Targets for Drug Development.

Kjell Fuxe1, Dasiel O Borroto-Escuela1.   

Abstract

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Year:  2016        PMID： 26657959      PMCID： PMC4677137          DOI： 10.1038/npp.2015.244

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


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  6 in total

Review 1.  Edward E. Smissman-Bristol-Myers Squibb Award Address. The role of concepts in structure-activity relationship studies of opioid ligands.

Authors:  P S Portoghese
Journal:  J Med Chem       Date:  1992-05-29       Impact factor: 7.446

Review 2.  Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field.

Authors:  Kjell Fuxe; Dasiel O Borroto-Escuela; Wilber Romero-Fernandez; Miklós Palkovits; Alexander O Tarakanov; Francisco Ciruela; Luigi F Agnati
Journal:  Neuropsychopharmacology       Date:  2013-09-06       Impact factor: 7.853

3.  Dopamine D2 receptors form higher order oligomers at physiological expression levels.

Authors:  Wen Guo; Eneko Urizar; Michaela Kralikova; Juan Carlos Mobarec; Lei Shi; Marta Filizola; Jonathan A Javitch
Journal:  EMBO J       Date:  2008-09-03       Impact factor: 11.598

Review 4.  Dopamine receptor heteromeric complexes and their emerging functions.

Authors:  Susan R George; Andras Kern; Roy G Smith; Rafael Franco
Journal:  Prog Brain Res       Date:  2014       Impact factor: 2.453

5.  Enhancement of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems. Relevance for neuroplasticity and depression.

Authors:  Dasiel O Borroto-Escuela; Mileidys Pérez-Alea; Manuel Narvaez; Alexander O Tarakanov; Giuseppa Mudó; Antonio Jiménez-Beristain; Luigi F Agnati; Francisco Ciruela; Natale Belluardo; Kjell Fuxe
Journal:  Biochem Biophys Res Commun       Date:  2015-05-06       Impact factor: 3.575

6.  Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.

Authors:  Yang Han; Irina S Moreira; Eneko Urizar; Harel Weinstein; Jonathan A Javitch
Journal:  Nat Chem Biol       Date:  2009-08-02       Impact factor: 15.040
  6 in total
  15 in total

Review 1.  Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders.

Authors:  Richard M Kostrzewa; Karolina Wydra; Malgorzata Filip; Cynthia A Crawford; Sanders A McDougall; Russell W Brown; Dasiel O Borroto-Escuela; Kjell Fuxe; Raul R Gainetdinov
Journal:  J Pharmacol Exp Ther       Date:  2018-06-19       Impact factor: 4.030

Review 2.  Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia.

Authors:  Dasiel O Borroto-Escuela; Julia Pintsuk; Thorsten Schäfer; Kristina Friedland; Luca Ferraro; Sergio Tanganelli; Fang Liu; Kjell Fuxe
Journal:  Ther Adv Psychopharmacol       Date:  2016-03-10

Review 3.  Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes.

Authors:  Dasiel O Borroto-Escuela; Karolina Wydra; Julia Pintsuk; Manuel Narvaez; Fidel Corrales; Magdalena Zaniewska; Luigi F Agnati; Rafael Franco; Sergio Tanganelli; Luca Ferraro; Malgorzata Filip; Kjell Fuxe
Journal:  Neural Plast       Date:  2016-10-30       Impact factor: 3.599

4.  Disturbances in the FGFR1-5-HT1A Heteroreceptor Complexes in the Raphe-Hippocampal 5-HT System Develop in a Genetic Rat Model of Depression.

Authors:  Dasiel O Borroto-Escuela; Caitlin M DuPont; Xiang Li; David Savelli; Davide Lattanzi; Ipsit Srivastava; Manuel Narváez; Michael Di Palma; Elisa Barbieri; Yuniesky Andrade-Talavera; Riccardo Cuppini; Yuji Odagaki; Miklos Palkovits; Patrizia Ambrogini; Maria Lindskog; Kjell Fuxe
Journal:  Front Cell Neurosci       Date:  2017-10-10       Impact factor: 5.505

Review 5.  Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease.

Authors:  Dasiel O Borroto-Escuela; Jens Carlsson; Patricia Ambrogini; Manuel Narváez; Karolina Wydra; Alexander O Tarakanov; Xiang Li; Carmelo Millón; Luca Ferraro; Riccardo Cuppini; Sergio Tanganelli; Fang Liu; Malgorzata Filip; Zaida Diaz-Cabiale; Kjell Fuxe
Journal:  Front Cell Neurosci       Date:  2017-02-21       Impact factor: 5.505

6.  Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition.

Authors:  Dasiel O Borroto-Escuela; Xiang Li; Alexander O Tarakanov; David Savelli; Manuel Narváez; Kirill Shumilov; Yuniesky Andrade-Talavera; Antonio Jimenez-Beristain; Bartosz Pomierny; Zaida Díaz-Cabiale; Riccardo Cuppini; Patrizia Ambrogini; Maria Lindskog; Kjell Fuxe
Journal:  ACS Omega       Date:  2017-08-22

7.  Hypothesis: The Psychedelic Ayahuasca Heals Traumatic Memories via a Sigma 1 Receptor-Mediated Epigenetic-Mnemonic Process.

Authors:  Antonio Inserra
Journal:  Front Pharmacol       Date:  2018-04-05       Impact factor: 5.810

8.  Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer.

Authors:  Dasiel O Borroto-Escuela; David Rodriguez; Wilber Romero-Fernandez; Jon Kapla; Mariama Jaiteh; Anirudh Ranganathan; Tzvetana Lazarova; Kjell Fuxe; Jens Carlsson
Journal:  Front Pharmacol       Date:  2018-08-30       Impact factor: 5.810

Review 9.  Emerging Role of (Endo)Cannabinoids in Migraine.

Authors:  Pinja Leimuranta; Leonard Khiroug; Rashid Giniatullin
Journal:  Front Pharmacol       Date:  2018-04-24       Impact factor: 5.810

Review 10.  Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment.

Authors:  Dasiel O Borroto-Escuela; Manuel Narváez; Patrizia Ambrogini; Luca Ferraro; Ismel Brito; Wilber Romero-Fernandez; Yuniesky Andrade-Talavera; Antonio Flores-Burgess; Carmelo Millon; Belen Gago; Jose Angel Narvaez; Yuji Odagaki; Miklos Palkovits; Zaida Diaz-Cabiale; Kjell Fuxe
Journal:  Molecules       Date:  2018-06-03       Impact factor: 4.411
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