Literature DB >> 26657953

Dynorphin, Dysphoria, and Dependence: the Stress of Addiction.

Charles Chavkin1, George F Koob2.   

Abstract

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Year:  2016        PMID： 26657953      PMCID： PMC4677142          DOI： 10.1038/npp.2015.258

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


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  6 in total

1.  Safety, tolerability, and pharmacokinetic evaluation of single- and multiple-ascending doses of a novel kappa opioid receptor antagonist LY2456302 and drug interaction with ethanol in healthy subjects.

Authors:  Stephen L Lowe; Conrad J Wong; Jennifer Witcher; Celedon R Gonzales; Gemma L Dickinson; Robert L Bell; Linda Rorick-Kehn; MaryAnn Weller; Randall R Stoltz; Jane Royalty; Sitra Tauscher-Wisniewski
Journal:  J Clin Pharmacol       Date:  2014-03-26       Impact factor: 3.126

Review 2.  Addiction as a stress surfeit disorder.

Authors:  George F Koob; Cara L Buck; Ami Cohen; Scott Edwards; Paula E Park; Joel E Schlosburg; Brooke Schmeichel; Leandro F Vendruscolo; Carrie L Wade; Timothy W Whitfield; Olivier George
Journal:  Neuropharmacology       Date:  2013-06-06       Impact factor: 5.250

3.  κ Opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake.

Authors:  Timothy W Whitfield; Joel E Schlosburg; Sunmee Wee; Adam Gould; Olivier George; Yanabel Grant; Eva R Zamora-Martinez; Scott Edwards; Elena Crawford; Leandro F Vendruscolo; George F Koob
Journal:  J Neurosci       Date:  2015-03-11       Impact factor: 6.167

Review 4.  The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors.

Authors:  M R Bruchas; B B Land; C Chavkin
Journal:  Brain Res       Date:  2009-08-28       Impact factor: 3.252

Review 5.  Development of κ opioid receptor antagonists.

Authors:  F Ivy Carroll; William A Carlezon
Journal:  J Med Chem       Date:  2013-02-14       Impact factor: 7.446

6.  Safety, tolerability, and clinical effect of low-dose buprenorphine for treatment-resistant depression in midlife and older adults.

Authors:  Jordan F Karp; Meryl A Butters; Amy E Begley; Mark D Miller; Eric J Lenze; Daniel M Blumberger; Benoit H Mulsant; Charles F Reynolds
Journal:  J Clin Psychiatry       Date:  2014-08       Impact factor: 4.384
  6 in total
  58 in total

1.  Association of variants of prodynorphin promoter 68-bp repeats in caucasians with opioid dependence diagnosis: Effect on age trajectory of heroin use.

Authors:  Vadim Yuferov; Matthew Randesi; Eduardo R Butelman; Wim van den Brink; Peter Blanken; Jan M van Ree; Jürg Ott; Mary Jeanne Kreek
Journal:  Neurosci Lett       Date:  2019-03-29       Impact factor: 3.046

2.  mTORC1 pathway is involved in the kappa opioid receptor activation-induced increase in excessive alcohol drinking in mice.

Authors:  Yan Zhou; Yupu Liang; Mary Jeanne Kreek
Journal:  Pharmacol Biochem Behav       Date:  2020-05-26       Impact factor: 3.533

Review 3.  Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development.

Authors:  George F Koob
Journal:  Pharmacol Rev       Date:  2021-01       Impact factor: 25.468

4.  Kappa-opioid antagonists as stress resilience medications for the treatment of alcohol use disorders.

Authors:  Charles Chavkin
Journal:  Neuropsychopharmacology       Date:  2018-03-27       Impact factor: 7.853

Review 5.  The Rise and Fall of Kappa-Opioid Receptors in Drug Abuse Research.

Authors:  Matthew L Banks
Journal:  Handb Exp Pharmacol       Date:  2020

6.  Projection-Specific Potentiation of Ventral Pallidal Glutamatergic Outputs after Abstinence from Cocaine.

Authors:  Liran A Levi; Kineret Inbar; Noa Nachshon; Nimrod Bernat; Ava Kamoun; Dorrit Inbar; Yonatan M Kupchik
Journal:  J Neurosci       Date:  2019-12-13       Impact factor: 6.167

Review 7.  Biased signalling: from simple switches to allosteric microprocessors.

Authors:  Jeffrey S Smith; Robert J Lefkowitz; Sudarshan Rajagopal
Journal:  Nat Rev Drug Discov       Date:  2018-01-05       Impact factor: 84.694

8.  Novel Dimethyltyrosine-Tetrahydroisoquinoline Peptidomimetics with Aromatic Tetrahydroisoquinoline Substitutions Show in Vitro Kappa and Mu Opioid Receptor Agonism.

Authors:  Deanna Montgomery; Jessica P Anand; Nicholas W Griggs; Thomas J Fernandez; Joshua G Hartman; Ashley A Sánchez-Santiago; Irina D Pogozheva; John R Traynor; Henry I Mosberg
Journal:  ACS Chem Neurosci       Date:  2019-07-01       Impact factor: 4.418

Review 9.  Targeting opioid dysregulation in depression for the development of novel therapeutics.

Authors:  Caroline A Browne; Irwin Lucki
Journal:  Pharmacol Ther       Date:  2019-04-30       Impact factor: 12.310

10.  Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion.

Authors:  Antony D Abraham; Selena S Schattauer; Kathryn L Reichard; Joshua H Cohen; Harrison M Fontaine; Allisa J Song; Salina D Johnson; Benjamin B Land; Charles Chavkin
Journal:  J Neurosci       Date:  2018-08-03       Impact factor: 6.167
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