Hisham Dokainish1, Koon Teo2, Jun Zhu3, Ambuj Roy4, Khalid F AlHabib5, Ahmed ElSayed6, Lia Palileo-Villaneuva7, Patricio Lopez-Jaramillo8, Kamilu Karaye9, Khalid Yusoff10, Andres Orlandini11, Karen Sliwa12, Charles Mondo13, Fernando Lanas14, Dorairaj Prabhakaran15, Amr Badr16, Mohamed Elmaghawry17, Albertino Damasceno18, Kemi Tibazarwa19, Emilie Belley-Cote2, Kumar Balasubramanian2, Magdi H Yacoub20, Mark D Huffman21, Karen Harkness2, Alex Grinvalds2, Robert McKelvie2, Salim Yusuf2. 1. Population Health Research Institute, McMaster University, Hamilton, Canada. Electronic address: hisham.dokainish@phri.ca. 2. Population Health Research Institute, McMaster University, Hamilton, Canada. 3. Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Beijing, China; Chinese Academy of Medical Sciences, Beijing, China. 4. All India Institute of Medical Science, New Delhi, India. 5. King Fahad Cardiac Center, King Saud University, Riyadh, Saudi Arabia. 6. AlShaab Teaching Hospital, Khartoum, Sudan. 7. University of the Philippines, Manila, Philippines. 8. Fundacion Oftalmologica de Santander, (FOSCAL) and Medical School, Universidad de Santander (UDES), Bucaramanga, Colombia. 9. Bayero University, Kano, Nigeria; Aminu Kano Teaching Hospital, Kano, Nigeria. 10. UiTM Selayang, Selangor University, Cheras, Malaysia; UCSI University, Cheras, Malaysia. 11. ECLA Foundation, Instituto Cardiovascular de Rosario, Argentina. 12. Hatter Institute for Cardiovascular Research in Africa, SAMRC, Faculty of Health Sciences, University of Cape Town, South Africa. 13. Mulago National Referral Hospital, Kampala, Uganda. 14. Universidad de La Frontera, Temuco, Chile. 15. Centre for Chronic Disease Control, New Delhi, India. 16. Hamad Medical Center, Doha, Qatar. 17. Aswan Heart Centre, Aswan, Egypt. 18. Eduardo Mondlane University, Maputo, Mozambique. 19. Department of Cardiovascular Medicine, Muhimbili National Hospital, Dar es Salaam, Tanzania. 20. Hamad Medical Center, Doha, Qatar; Aswan Heart Centre, Aswan, Egypt. 21. Northwestern University Feinberg School of Medicine, Chicago, USA.
Abstract
BACKGROUND: There are few data on heart failure (HF) patients from Africa, Asia, the Middle East and South America. METHODS: INTER-CHF is a prospective study that enrolled HF patients in 108 centers in 16 countries from 2012 to 2014. Consecutive ambulatory or hospitalized adult patients with HF were enrolled. Baseline data were recorded on sociodemographics, clinical characteristics, HF etiology and treatments. Age- and sex-adjusted results are reported. RESULTS: We recruited 5813 HF patients: mean(SE) age=59(0.2)years, 39% female, 65% outpatients, 31% from rural areas, 26% with HF with preserved ejection fraction, with 1294 from Africa, 2661 from Asia, 1000 from the Middle-East, and 858 from South America. Participants from Africa-closely followed by Asians-were younger, had lower literacy levels, and were less likely to have health or medication insurance or be on beta-blockers compared with participants from other regions, but were most likely to be in NYHA class IV. Participants from South America were older, had higher insurance and literacy levels, and, along with Middle Eastern participants, were more likely to be on beta-blockers, but had the lowest proportion in NYHA IV. Ischemic heart disease was the most common HF etiology in all regions except Africa where hypertensive heart disease was most common. CONCLUSIONS: INTER-CHF describes significant regional variability in socioeconomic and clinical factors, etiologies and treatments in HF patients from Africa, Asia, the Middle East and South America. Opportunities exist for improvement in health/medication insurance rates and proportions of patients on beta blockers, particularly in Africa and Asia.
BACKGROUND: There are few data on heart failure (HF) patients from Africa, Asia, the Middle East and South America. METHODS: INTER-CHF is a prospective study that enrolled HF patients in 108 centers in 16 countries from 2012 to 2014. Consecutive ambulatory or hospitalized adult patients with HF were enrolled. Baseline data were recorded on sociodemographics, clinical characteristics, HF etiology and treatments. Age- and sex-adjusted results are reported. RESULTS: We recruited 5813 HF patients: mean(SE) age=59(0.2)years, 39% female, 65% outpatients, 31% from rural areas, 26% with HF with preserved ejection fraction, with 1294 from Africa, 2661 from Asia, 1000 from the Middle-East, and 858 from South America. Participants from Africa-closely followed by Asians-were younger, had lower literacy levels, and were less likely to have health or medication insurance or be on beta-blockers compared with participants from other regions, but were most likely to be in NYHA class IV. Participants from South America were older, had higher insurance and literacy levels, and, along with Middle Eastern participants, were more likely to be on beta-blockers, but had the lowest proportion in NYHA IV. Ischemic heart disease was the most common HF etiology in all regions except Africa where hypertensiveheart disease was most common. CONCLUSIONS: INTER-CHF describes significant regional variability in socioeconomic and clinical factors, etiologies and treatments in HF patients from Africa, Asia, the Middle East and South America. Opportunities exist for improvement in health/medication insurance rates and proportions of patients on beta blockers, particularly in Africa and Asia.
Authors: Santanu Guha; S Harikrishnan; Saumitra Ray; Rishi Sethi; S Ramakrishnan; Suvro Banerjee; V K Bahl; K C Goswami; Amal Kumar Banerjee; S Shanmugasundaram; P G Kerkar; Sandeep Seth; Rakesh Yadav; Aditya Kapoor; Ajaykumar U Mahajan; P P Mohanan; Sundeep Mishra; P K Deb; C Narasimhan; A K Pancholia; Ajay Sinha; Akshyaya Pradhan; R Alagesan; Ambuj Roy; Amit Vora; Anita Saxena; Arup Dasbiswas; B C Srinivas; B P Chattopadhyay; B P Singh; J Balachandar; K R Balakrishnan; Brian Pinto; C N Manjunath; Charan P Lanjewar; Dharmendra Jain; Dipak Sarma; G Justin Paul; Geevar A Zachariah; H K Chopra; I B Vijayalakshmi; J A Tharakan; J J Dalal; J P S Sawhney; Jayanta Saha; Johann Christopher; K K Talwar; K Sarat Chandra; K Venugopal; Kajal Ganguly; M S Hiremath; Milind Hot; Mrinal Kanti Das; Neil Bardolui; Niteen V Deshpande; O P Yadava; Prashant Bhardwaj; Pravesh Vishwakarma; Rajeeve Kumar Rajput; Rakesh Gupta; S Somasundaram; S N Routray; S S Iyengar; G Sanjay; Satyendra Tewari; Sengottuvelu G; Soumitra Kumar; Soura Mookerjee; Tiny Nair; Trinath Mishra; U C Samal; U Kaul; V K Chopra; V S Narain; Vimal Raj; Yash Lokhandwala Journal: Indian Heart J Date: 2018-06-08
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