Literature DB >> 2665741

Immunoreactive endothelin in rat kidney inner medulla: marked decrease in spontaneously hypertensive rats.

K Kitamura1, T Tanaka, J Kato, T Ogawa, T Eto, K Tanaka.   

Abstract

Using a specific and sensitive radioimmunoassay for endothelin, the regional distribution and molecular form of endothelin was investigated in rat tissue. The highest concentration was observed in the inner medulla of the kidney (8.7 +/- 2.2 pg/mg wet weight). On two kinds of reverse phase high performance liquid chromatography, immunoreactive endothelin in the inner medulla of the kidney was separated into two peaks at positions where authentic porcine/human and putative rat/human endothelin eluted. Furthermore, the concentration of immunoreactive endothelin in the inner medulla of the kidney was remarkably decreased in spontaneously hypertensive rats (SHR) compared with normotensive control Wistar Kyoto rats (WKY) but no difference was observed in lung immunoreactive endothelin.

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Year:  1989        PMID： 2665741     DOI： 10.1016/0006-291x(89)91958-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  17 in total

1.  Endothelin-1 mRNA expression in the rat kidney.

Authors:  D J Nunez; E A Taylor; V M Oh; J P Schofield; M J Brown
Journal:  Biochem J       Date:  1991-05-01       Impact factor: 3.857

Review 2.  Physiology of endothelin and the kidney.

Authors:  Donald E Kohan; Edward W Inscho; Donald Wesson; David M Pollock
Journal:  Compr Physiol       Date:  2011-04       Impact factor: 9.090

Review 3.  Regulation of blood pressure and salt homeostasis by endothelin.

Authors:  Donald E Kohan; Noreen F Rossi; Edward W Inscho; David M Pollock
Journal:  Physiol Rev       Date:  2011-01       Impact factor: 37.312

4.  Extracellular signal-regulated kinases 1/2 signaling pathways are not involved in endothelin regulation of mouse inner medullary collecting duct nitric oxide production.

Authors:  Kelly A Hyndman; Alexander H MacDonell; Jennifer S Pollock
Journal:  Life Sci       Date:  2012-10-15       Impact factor: 5.037

5.  Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention.

Authors:  Dowhan Ahn; Yuqiang Ge; Peter K Stricklett; Pritmohinder Gill; Deborah Taylor; Alisa K Hughes; Masashi Yanagisawa; Lance Miller; Raoul D Nelson; Donald E Kohan
Journal:  J Clin Invest       Date:  2004-08       Impact factor: 14.808

6.  Endothelin and endothelium-derived relaxing factor control of basal renovascular tone in hydronephrotic rat kidneys.

Authors:  E Gulbins; J Hoffend; A P Zou; M S Dietrich; K Schlottmann; A Cavarape; M Steinhausen
Journal:  J Physiol       Date:  1993-09       Impact factor: 5.182

7.  Aldosterone modulates steroid receptor binding to the endothelin-1 gene (edn1).

Authors:  Lisa R Stow; Michelle L Gumz; I Jeanette Lynch; Megan M Greenlee; Alicia Rudin; Brian D Cain; Charles S Wingo
Journal:  J Biol Chem       Date:  2009-07-28       Impact factor: 5.157

8.  Contribution of endothelin A receptors in endothelin 1-dependent natriuresis in female rats.

Authors:  Daisuke Nakano; David M Pollock
Journal:  Hypertension       Date:  2008-12-22       Impact factor: 10.190

Review 9.  Role of collecting duct endothelin in control of renal function and blood pressure.

Authors:  Donald E Kohan
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2013-08-28       Impact factor: 3.619

10.  Renal medullary ETB receptors produce diuresis and natriuresis via NOS1.

Authors:  Daisuke Nakano; Jennifer S Pollock; David M Pollock
Journal:  Am J Physiol Renal Physiol       Date:  2008-02-27
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