Literature DB >> 26651358

Interaction between Tea Polyphenols and Bile Acid Inhibits Micellar Cholesterol Solubility.

Kazuki Ogawa1, Sayumi Hirose1, Satoshi Nagaoka1, Emiko Yanase1.   

Abstract

The molecular mechanism by which tea polyphenols decrease the micellar solubility of cholesterol is not completely clear. To clarify this mechanism, this study investigated the interaction between tea polyphenols (catechins and oolongtheanins) and cholesterol micelles. A nuclear magnetic resonance (NMR) study was performed on a micellar solution containing taurocholic acid and epigallocatechin gallate (EGCg), and high-performance liquid chromatography (HPLC) analysis was carried out on the precipitate and the supernatant that formed when EGCg was added to a cholesterol-micelle solution. The data indicated a regiospecific interaction of EGCg with taurocholic acid. Therefore, the ability of EGCg to lower the solubility of phosphatidylcholine (PC) and cholesterol in micellar solutions can be attributed to their elimination from the micelles due to interaction between taurocholic acids and EGCg.

Entities:  

Keywords:  catechin; cholesterol; micelle; oolongtheanin

Mesh：

Substances：

Year:  2015        PMID： 26651358     DOI： 10.1021/acs.jafc.5b05088

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN： 0021-8561            Impact factor:   5.279


  11 in total

1.  Green Tea Polyphenol EGCG Alleviates Metabolic Abnormality and Fatty Liver by Decreasing Bile Acid and Lipid Absorption in Mice.

Authors:  Jinbao Huang; Simin Feng; Anna Liu; Zhuqing Dai; Hong Wang; Kenneth Reuhl; Wenyun Lu; Chung S Yang
Journal:  Mol Nutr Food Res       Date:  2018-01-29       Impact factor: 5.914

2.  Antioxidant and anti-inflammatory effects of polyphenols extracted from Ilex latifolia Thunb.

Authors:  Tian-Tian Zhang; Ting Hu; Jian-Guo Jiang; Jing-Wen Zhao; Wei Zhu
Journal:  RSC Adv       Date:  2018-02-14       Impact factor: 4.036

3.  Mitigation of nonalcoholic fatty liver disease in high-fat-fed mice by the combination of decaffeinated green tea extract and voluntary exercise.

Authors:  Weslie Y Khoo; Benjamin J Chrisfield; Sudathip Sae-Tan; Joshua D Lambert
Journal:  J Nutr Biochem       Date:  2019-10-27       Impact factor: 6.048

4.  Spirogyra neglecta inhibits the absorption and synthesis of cholesterol in vitro.

Authors:  Acharaporn Duangjai; Nanteetip Limpeanchob; Kanittaporn Trisat; Doungporn Amornlerdpison
Journal:  Integr Med Res       Date:  2016-08-22

5.  Defining Lineage-Specific Membrane Fluidity Signatures that Regulate Adhesion Kinetics.

Authors:  Takahisa Matsuzaki; Shinya Matsumoto; Toshiharu Kasai; Emi Yoshizawa; Satoshi Okamoto; Hiroshi Y Yoshikawa; Hideki Taniguchi; Takanori Takebe
Journal:  Stem Cell Reports       Date:  2018-09-06       Impact factor: 7.765

6.  Catechins Controlled Bioavailability of Benzo[a]pyrene (B[α]P) from the Gastrointestinal Tract to the Brain towards Reducing Brain Toxicity Using the In Vitro Bio-Mimic System Coupled with Sequential Co-Cultures.

Authors:  Kang-Hyun Jeong; Hyun Jeong Lee; Tae-Sik Park; Soon-Mi Shim
Journal:  Molecules       Date:  2019-06-10       Impact factor: 4.411

7.  In vitro lipid-lowering properties of the fruits of two bignay [Antidesma bunius (L.) Spreng] cultivars as affected by maturity stage and thermal processing.

Authors:  Bince Russo A Crieta; Arvin Paul P Tuaño; Mary Ann O Torio; Jeric C Villanueva; Prince Joseph V Gaban; Katherine Ann T Castillo-Israel
Journal:  Food Chem (Oxf)       Date:  2021-03-25

8.  Regular exercise combined with ferulic acid exhibits antiobesity effect and regulates metabolic profiles in high-fat diet-induced mice.

Authors:  Ou Wang; Nanhai Zhang; Chao Han; Jian Huang
Journal:  Front Nutr       Date:  2022-07-27

9.  The Powdering Process with a Set of Ceramic Mills for Green Tea Promoted Catechin Extraction and the ROS Inhibition Effect.

Authors:  Kouki Fujioka; Takeo Iwamoto; Hidekazu Shima; Keiko Tomaru; Hideki Saito; Masaki Ohtsuka; Akihiro Yoshidome; Yuri Kawamura; Yoshinobu Manome
Journal:  Molecules       Date:  2016-04-11       Impact factor: 4.411

Review 10.  Mechanisms of Interactions between Bile Acids and Plant Compounds-A Review.

Authors:  Susanne Naumann; Dirk Haller; Peter Eisner; Ute Schweiggert-Weisz
Journal:  Int J Mol Sci       Date:  2020-09-05       Impact factor: 5.923
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