Literature DB >> 26651127

Assessment of therapeutic options for reducing alkali burn-induced corneal neovascularization and inflammation.

Alina Bakunowicz-Łazarczyk1, Beata Urban2.   

Abstract

This article aims to review and provide the current knowledge of the possibilities of topical treatment of corneal neovascularization due to alkali burns, evidenced by laboratory experiments, in vitro studies, and clinical trials published in the specialized literature. Authors present clinically relevant treatment of corneal neovascularization used in clinical practice, potential antiangiogenic topical therapeutics against corneal neovascularization, which are under investigation, and anti-angiogenic gene-therapy.
Copyright © 2015 Medical University of Bialystok. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

Entities:  

Keywords:  Alkali burn; Corneal neovascularization; Treatment

Mesh：

Substances：

Year:  2015        PMID： 26651127     DOI： 10.1016/j.advms.2015.10.003

Source DB:  PubMed          Journal:  Adv Med Sci        ISSN： 1896-1126            Impact factor:   3.287


  7 in total

Review 1.  The molecular mechanisms of action of PPAR-γ agonists in the treatment of corneal alkali burns (Review).

Authors:  Hongyan Zhou; Wensong Zhang; Miaomiao Bi; Jie Wu
Journal:  Int J Mol Med       Date:  2016-08-04       Impact factor: 4.101

2.  Xenofree generation of limbal stem cells for ocular surface advanced cell therapy.

Authors:  Nuria Nieto-Nicolau; Eva M Martínez-Conesa; Alba M Velasco-García; Caterina Aloy-Reverté; Anna Vilarrodona; Ricardo P Casaroli-Marano
Journal:  Stem Cell Res Ther       Date:  2019-12-04       Impact factor: 6.832

3.  Subconjunctival Injection of Regulatory T Cells Potentiates Corneal Healing Via Orchestrating Inflammation and Tissue Repair After Acute Alkali Burn.

Authors:  Dan Yan; Fei Yu; Liangbo Chen; Qinke Yao; Chenxi Yan; Siyi Zhang; Nianxuan Wu; Danni Gong; Hao Sun; Yao Fu; Chunyi Shao
Journal:  Invest Ophthalmol Vis Sci       Date:  2020-12-01       Impact factor: 4.799

4.  Pharmacological Inhibition of Glutaminase 1 Attenuates Alkali-Induced Corneal Neovascularization by Modulating Macrophages.

Authors:  Yifan Feng; Xi Yang; Jinhai Huang; Minqian Shen; Liyang Wang; Xiuping Chen; Yuanzhi Yuan; Chunqiong Dong; Xiaoping Ma; Fei Yuan
Journal:  Oxid Med Cell Longev       Date:  2022-03-19       Impact factor: 6.543

5.  Using Convolutional Neural Network as a Statistical Algorithm to Explore the Therapeutic Effect of Insulin Liposomes on Corneal Inflammation.

Authors:  Yukun Liao; Huiting Jiang; Yangrui Du; Xiaojing Xiong; Yu Zhang; Zhiyu Du
Journal:  Comput Intell Neurosci       Date:  2022-07-31

6.  Effect of Tauroursodeoxycholic Acid on Inflammation after Ocular Alkali Burn.

Authors:  Yanqiao Huang; Lixia Lin; Yao Yang; Fang Duan; Miner Yuan; Bingsheng Lou; Xiaofeng Lin
Journal:  Int J Mol Sci       Date:  2022-10-03       Impact factor: 6.208

7.  The long-term effect of tacrolimus on alkali burn-induced corneal neovascularization and inflammation surpasses that of anti-vascular endothelial growth factor.

Authors:  Ling Chen; Jing Zhong; Saiqun Li; Weihua Li; Bowen Wang; Yuqing Deng; Jin Yuan
Journal:  Drug Des Devel Ther       Date:  2018-09-12       Impact factor: 4.162
  7 in total

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