PURPOSE: To report a case of panuveitis, retinal vasculitis, and optic disk granuloma due to sarcoidosis. METHODS: Case report and literature review. RESULTS: A 26-year-old previously healthy African American male presented with four months of gradual progressive visual decline in the right eye. Clinical examination revealed severe panuveitis, retinal vasculitis, and large optic nerve mass lesion. Diffuse supraclavicular lymphadenopathy was also present. Histopathologic examination of the lymph node biopsy revealed granulomatous inflammation with some areas of caseous necrosis consistent with sarcoidosis. CONCLUSION: Sarcoidosis is a common cause of uveitis and retinal vasculitis. In rare cases, an optic disk granuloma may occur and can be treated with immunosuppressive therapy.
PURPOSE: To report a case of panuveitis, retinal vasculitis, and optic disk granuloma due to sarcoidosis. METHODS: Case report and literature review. RESULTS: A 26-year-old previously healthy African American male presented with four months of gradual progressive visual decline in the right eye. Clinical examination revealed severe panuveitis, retinal vasculitis, and large optic nerve mass lesion. Diffuse supraclavicular lymphadenopathy was also present. Histopathologic examination of the lymph node biopsy revealed granulomatous inflammation with some areas of caseous necrosis consistent with sarcoidosis. CONCLUSION:Sarcoidosis is a common cause of uveitis and retinal vasculitis. In rare cases, an optic disk granuloma may occur and can be treated with immunosuppressive therapy.
Authors: Jacob J Koczman; Jacinthe Rouleau; Morgan Gaunt; Randy H Kardon; Michael Wall; Andrew G Lee Journal: Semin Ophthalmol Date: 2008 May-Jun Impact factor: 1.975