Literature DB >> 26650445

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes.

Stephen Ph Alexander1, Doriano Fabbro2, Eamonn Kelly3, Neil Marrion3, John A Peters4, Helen E Benson5, Elena Faccenda5, Adam J Pawson5, Joanna L Sharman5, Christopher Southan5, Jamie A Davies5.   

Abstract

The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13354/full. G protein-coupled receptors are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
© 2015 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.

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Year:  2015        PMID: 26650445      PMCID: PMC4718211          DOI: 10.1111/bph.13354

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  511 in total

1.  Metabolic profiling of murine plasma reveals eicosapentaenoic acid metabolites protecting against endothelial activation and atherosclerosis.

Authors:  Yajin Liu; Xuan Fang; Xu Zhang; Jing Huang; Jinlong He; Liyuan Peng; Chenji Ye; Yingmei Wang; Fengxia Xue; Ding Ai; Dan Li; Yi Zhu
Journal:  Br J Pharmacol       Date:  2017-09-05       Impact factor: 8.739

2.  Effects of centrally administered endocannabinoids and opioids on orofacial pain perception in rats.

Authors:  Marek Zubrzycki; Anna Janecka; Andreas Liebold; Mechthild Ziegler; Maria Zubrzycka
Journal:  Br J Pharmacol       Date:  2017-08-30       Impact factor: 8.739

Review 3.  P2X receptor channels in chronic pain pathways.

Authors:  Louis-Philippe Bernier; Ariel R Ase; Philippe Séguéla
Journal:  Br J Pharmacol       Date:  2017-08-17       Impact factor: 8.739

4.  Protective effects of dioscin against cisplatin-induced nephrotoxicity via the microRNA-34a/sirtuin 1 signalling pathway.

Authors:  Yimeng Zhang; Xufeng Tao; Lianhong Yin; Lina Xu; Youwei Xu; Yan Qi; Xu Han; Shasha Song; Yanyan Zhao; Yuan Lin; Kexin Liu; Jinyong Peng
Journal:  Br J Pharmacol       Date:  2017-07-05       Impact factor: 8.739

5.  Pharmacokinetics and safety of the anti-human cytomegalovirus drug letermovir in subjects with hepatic impairment.

Authors:  Dirk Kropeit; David McCormick; Katharina Erb-Zohar; Valentin S Moiseev; Zhanna D Kobalava; Hans-Peter Stobernack; Holger Zimmermann; Helga Rübsamen-Schaeff
Journal:  Br J Clin Pharmacol       Date:  2017-08-27       Impact factor: 4.335

6.  Evaluation of the pharmacokinetic drug interaction potential of tivantinib (ARQ 197) using cocktail probes in patients with advanced solid tumours.

Authors:  Masaya Tachibana; Kyriakos P Papadopoulos; John H Strickler; Igor Puzanov; Roohi Gajee; Yibin Wang; Hamim Zahir
Journal:  Br J Clin Pharmacol       Date:  2017-10-29       Impact factor: 4.335

7.  Dose-dependent acute liver injury with hypersensitivity features in humans due to a novel microsomal prostaglandin E synthase 1 inhibitor.

Authors:  Yan Jin; Arie Regev; Jeanelle Kam; Krista Phipps; Claire Smith; Judith Henck; Kristina Campanale; Leijun Hu; D Greg Hall; Xiao Yan Yang; Masako Nakano; Terry Ann McNearney; Jack Uetrecht; William Landschulz
Journal:  Br J Clin Pharmacol       Date:  2017-10-08       Impact factor: 4.335

8.  Implication of in vivo circulating fibrocytes ablation in experimental pulmonary hypertension murine model.

Authors:  Vandana S Nikam; Sandeep Nikam; Akyl Sydykov; Katrin Ahlbrecht; Rory E Morty; Werner Seeger; Robert Voswinckel
Journal:  Br J Pharmacol       Date:  2020-04-12       Impact factor: 8.739

9.  Utility of serum anti-cetuximab immunoglobulin E levels to identify patients at a high risk of severe hypersensitivity reaction to cetuximab.

Authors:  Benoît Dupont; Delphine Mariotte; Audrey E Dugué; Bénédicte Clarisse; Jean-Michel Grellard; Emmanuel Babin; Bruno Chauffert; Stéphanie Dakpé; Cristian Moldovan; Karine Bouhier-Leporrier; Jean-Marie Reimund; Frederic Di Fiore; Sylvie Zanetta; Audrey Mailliez; Pascal Do; Annie Peytier; Marie-Pierre Galais; Carmen Florescu; Roland Schott; Brigitte Le Mauff; Radj Gervais
Journal:  Br J Clin Pharmacol       Date:  2016-10-24       Impact factor: 4.335

10.  Role of the nicotinic acetylcholine receptor α3 subtype in vascular inflammation.

Authors:  Cui Yang; Zhengtao Li; Saimei Yan; Yonghui He; Rong Dai; George Pek-Heng Leung; Shitian Pan; Jinyan Yang; Rong Yan; Guanhua Du
Journal:  Br J Pharmacol       Date:  2016-09-29       Impact factor: 8.739

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