Literature DB >> 26649597

Horse Allergy: Curly Horses Allow Horse Allergic Riders To Ride Again.

W Mitlehner1, H C Mitlehner2, B Niggemann3.   

Abstract

To test the hypothesis that so called hypoallergenic horses (Curly horses) allow horse allergic riders to ride again, we investigated 40 horse allergic riders in a period of 37 months.
Methods: We tested these patients (pts.) by skin prick test (SPT) with different non-curly and Curly horses and studied the riding hours and horse brushing by measurements of peak expiratory flow (PEF) and Tiffeneau tests (FEV1) as well as peak nasal inspiratory flow (PNIF) over 12 months. The results in 37/40 pts. showed no relevant reactions of the lower airways or nasal flow. Only in 3/40 patients an initial significant fall of FEV1 was observed, reversed by a single inhalation of salbutamol and not repeated despite further riding contact. In contrast to other allergic events (e. g. baker's asthma) a further and regular contact with these horses abolished the mild allergic reactions of the start period of contact. This may be due to hypoallergenic properties of these horses, whose test material produces weaker reactions in the SPT than that of normal horses. After a period of three years, a loss of reactivity to normal horses could be confirmed in some of the riders.
Conclusion: The tested purebreed Curly horses may be a suitable alternative for horse allergic riders if the methodological precautions of this study are followed. © Georg Thieme Verlag KG Stuttgart · New York.

Entities:  

Year:  2015        PMID: 26649597     DOI: 10.1055/s-0034-1393396

Source DB:  PubMed          Journal:  Pneumologie        ISSN: 0934-8387


  3 in total

1.  A missense variant in the coil1A domain of the keratin 25 gene is associated with the dominant curly hair coat trait (Crd) in horse.

Authors:  Caroline Morgenthaler; Mathieu Diribarne; Aurélien Capitan; Rachel Legendre; Romain Saintilan; Maïlys Gilles; Diane Esquerré; Rytis Juras; Anas Khanshour; Laurent Schibler; Gus Cothran
Journal:  Genet Sel Evol       Date:  2017-11-15       Impact factor: 4.297

2.  Lower allergen levels in hypoallergenic Curly Horses? A comparison among breeds by measurements of horse allergens in hair and air samples.

Authors:  Eva Zahradnik; Bente Janssen-Weets; Ingrid Sander; Benjamin Kendzia; Wolfgang Mitlehner; Caroline May; Monika Raulf
Journal:  PLoS One       Date:  2018-12-12       Impact factor: 3.240

3.  Levels of horse allergen Equ c 4 in dander and saliva from ten horse breeds.

Authors:  Susanne Victor; Jonas Binnmyr; Erik Lampa; Anna Rask-Andersen; Lena Elfman
Journal:  Clin Exp Allergy       Date:  2019-02-27       Impact factor: 5.018

  3 in total

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