| Literature DB >> 26648627 |
Brendan J McMullan1, Mona Mostaghim1.
Abstract
Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and excellent tissue penetration. It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used in preference to other macrolides for some sexually transmitted and enteric infections. Azithromycin has additional immunomodulatory effects and has been used in chronic respiratory inflammatory diseases for this purpose. Potential major adverse effects include cardiovascular arrhythmias and hearing loss. Macrolide resistance is also a problem, as are interactions with commonly prescribed drugs.Entities:
Keywords: antibiotic resistance; azithromycin; immunomodulators; macrolide antibiotics
Year: 2015 PMID: 26648627 PMCID: PMC4653965 DOI: 10.18773/austprescr.2015.030
Source DB: PubMed Journal: Aust Prescr ISSN: 0312-8008