Literature DB >> 26647619

PHARMACOLOGICAL ACTIVITIES OF PROTOCATECHUIC ACID.

Abida Kalsoom Khan, Rehana Rashid, Nighat Fatima, Sadaf Mahmood, Sadullah Mir, Sara Khan, Nyla Jabeen, Ghulam Murtaza.   

Abstract

Protocatechuic acid (3,4-dihydroxybenzoic acid, PCA) is a simple phenolic acid. It is found in a large variety of edible plants and possesses various pharmacological activities. This article aims to review the modern trends in phytochemical isolation and extraction of PCA from plants and other natural resources. Moreover, this article also encompasses pharmacological and biological activities of PCA. It is well known to have anti-inflammatory, antioxidant, anti-hyperglycemia, antibacterial, anticancer, anti-ageing, anti-athro- genic, anti-tumoral, anti-asthma, antiulcer, antispasmodic and neurological properties.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 26647619

Source DB:  PubMed          Journal:  Acta Pol Pharm        ISSN: 0001-6837            Impact factor:   0.330


  25 in total

1.  Molecular dynamics, MMGBSA, and docking studies of natural products conjugated to tumor-targeted peptide for targeting BRAF V600E and MERTK receptors.

Authors:  Dominic J Lambo; Charlotta G Lebedenko; Paige A McCallum; Ipsita A Banerjee
Journal:  Mol Divers       Date:  2022-05-03       Impact factor: 2.943

2.  Protocatechuic Acid as a Topical Antimicrobial for Surgical Skin Antisepsis: Preclinical Investigations.

Authors:  Omid Jalali; Molly Best; Alison Wong; Brett Schaeffer; Brendon Bauer; Lanny Johnson
Journal:  JB JS Open Access       Date:  2020-06-26

3.  Reduced Bacterial Burden of the Skin Surrounding the Shoulder Joint Following Topical Protocatechuic Acid Application: Results of a Pilot Study.

Authors:  Omid Jalali; Molly Best; Alison Wong; Brett Schaeffer; Brendon Bauer; Lanny Johnson
Journal:  JB JS Open Access       Date:  2020-07-17

4.  Combined Effects of Protocatechuic Acid and 5-Fluorouracil on p53 Gene Expression and Apoptosis in Gastric Adenocarcinoma Cells.

Authors:  Zahra Motamedi; Sayed Asadollah Amini; Elham Raeisi; Yves Lemoigne; Esfandiar Heidarian
Journal:  Turk J Pharm Sci       Date:  2020-12-23

5.  Alkyl Protocatechuate-Loaded Nanostructured Lipid Systems as a Treatment Strategy for Paracoccidioides brasiliensis and Paracoccidioides lutzii In Vitro.

Authors:  Kaila P Medina-Alarcón; Junya L Singulani; Aline R Voltan; Janaina C O Sardi; Maicon S Petrônio; Mariana B Santos; Carlos R Polaquini; Luis O Regasini; Vanderlan S Bolzani; Dulce H S da Silva; Marlus Chorilli; Maria J S Mendes-Giannini; Ana M Fusco-Almeida
Journal:  Front Microbiol       Date:  2017-06-12       Impact factor: 5.640

6.  Protective Effect of Protocatechuic Acid on TNBS-Induced Colitis in Mice Is Associated with Modulation of the SphK/S1P Signaling Pathway.

Authors:  Irene Crespo; Beatriz San-Miguel; José Luis Mauriz; Juan José Ortiz de Urbina; Mar Almar; María Jesús Tuñón; Javier González-Gallego
Journal:  Nutrients       Date:  2017-03-16       Impact factor: 5.717

7.  Protocatechuic Acid Attenuates Trabecular Bone Loss in Ovariectomized Mice.

Authors:  Seon-A Jang; Hae Seong Song; Jeong Eun Kwon; Hyun Jin Baek; Hyun Jung Koo; Eun-Hwa Sohn; Sung Ryul Lee; Se Chan Kang
Journal:  Oxid Med Cell Longev       Date:  2018-07-29       Impact factor: 6.543

8.  Ultrasound-Assisted Extraction and Identification of Natural Antioxidants from the Fruit of Melastoma sanguineum Sims.

Authors:  Tong Zhou; Dong-Ping Xu; Sheng-Jun Lin; Ya Li; Jie Zheng; Yue Zhou; Jiao-Jiao Zhang; Hua-Bin Li
Journal:  Molecules       Date:  2017-02-18       Impact factor: 4.411

9.  Enhanced Activity and Sustained Release of Protocatechuic Acid, a Natural Antibacterial Agent, from Hybrid Nanoformulations with Zinc Oxide Nanoparticles.

Authors:  Khaled AbouAitah; Urszula Piotrowska; Jacek Wojnarowicz; Anna Swiderska-Sroda; Ahmed H H El-Desoky; Witold Lojkowski
Journal:  Int J Mol Sci       Date:  2021-05-18       Impact factor: 5.923

10.  Effects of Protocatechuic Acid (PCA) on Global Cerebral Ischemia-Induced Hippocampal Neuronal Death.

Authors:  A Ra Kho; Bo Young Choi; Song Hee Lee; Dae Ki Hong; Sang Hwon Lee; Jeong Hyun Jeong; Kyoung-Ha Park; Hong Ki Song; Hui Chul Choi; Sang Won Suh
Journal:  Int J Mol Sci       Date:  2018-05-09       Impact factor: 5.923

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.