Literature DB >> 26647001

68Ga-NOTA-Exendin-4 PET/CT in Localization of an Occult Insulinoma and Appearance of Coexisting Esophageal Carcinoma.

Yaping Luo1, Naishi Li, Dale O Kiesewetter, Xiaoyuan Chen, Fang Li.   

Abstract

A 61-year-old woman with biochemically proven endogenous hyperinsulinemic hypoglycemia and negative conventional imaging underwent 68Ga-NOTA-exendin-4 PET/CT for localization of insulinoma. Focal intense radioactivity in the tail of the pancreas was observed that was subsequently confirmed as insulinoma pathologically after surgical resection. In addition, esophageal carcinoma with lymph node and hepatic metastases was found by FDG PET/CT in the same patient. Neither the primary carcinoma nor the metastases showed increased radioactivity on 68Ga-NOTA-exendin-4 PET/CT.

Entities:  

Mesh:

Substances:

Year:  2016        PMID: 26647001      PMCID: PMC4779726          DOI: 10.1097/RLU.0000000000001087

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN: 0363-9762            Impact factor:   7.794


  9 in total

1.  68Ga-NOTA-exendin-4 PET/CT in detection of occult insulinoma and evaluation of physiological uptake.

Authors:  Yaping Luo; Miao Yu; QingQing Pan; Wenming Wu; Taiping Zhang; Dale O Kiesewetter; Zhaohui Zhu; Fang Li; Xiaoyuan Chen; Yupei Zhao
Journal:  Eur J Nucl Med Mol Imaging       Date:  2014-11-15       Impact factor: 9.236

2.  Glucagon-like peptide 1-receptor scans to localize occult insulinomas.

Authors:  Damian Wild; Helmut Mäcke; Emanuel Christ; Beat Gloor; Jean Claude Reubi
Journal:  N Engl J Med       Date:  2008-08-14       Impact factor: 91.245

3.  Localization of Hidden Insulinomas with ⁶⁸Ga-DOTA-Exendin-4 PET/CT: A Pilot Study.

Authors:  Kwadwo Antwi; Melpomeni Fani; Guillaume Nicolas; Christof Rottenburger; Tobias Heye; Jean Claude Reubi; Beat Gloor; Emanuel Christ; Damian Wild
Journal:  J Nucl Med       Date:  2015-05-21       Impact factor: 10.057

Review 4.  Concomitant expression of several peptide receptors in neuroendocrine tumours: molecular basis for in vivo multireceptor tumour targeting.

Authors:  Jean Claude Reubi; Beatrice Waser
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-04-18       Impact factor: 9.236

5.  GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting.

Authors:  Meike Körner; Martin Stöckli; Beatrice Waser; Jean Claude Reubi
Journal:  J Nucl Med       Date:  2007-05       Impact factor: 10.057

6.  Glucagon-like peptide-1 receptor imaging for localization of insulinomas.

Authors:  Emanuel Christ; Damian Wild; Flavio Forrer; Michael Brändle; Rahel Sahli; Thomas Clerici; Beat Gloor; Ferdinand Martius; Helmut Maecke; Jean Claude Reubi
Journal:  J Clin Endocrinol Metab       Date:  2009-10-09       Impact factor: 5.958

7.  Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study.

Authors:  Emanuel Christ; Damian Wild; Susanne Ederer; Martin Béhé; Guillaume Nicolas; Martyn E Caplin; Michael Brändle; Thomas Clerici; Stefan Fischli; Christoph Stettler; Peter J Ell; Jochen Seufert; Beat Gloor; Aurel Perren; Jean Claude Reubi; Flavio Forrer
Journal:  Lancet Diabetes Endocrinol       Date:  2013-07-25       Impact factor: 32.069

8.  Glucagon-like peptide-1 receptor overexpression in cancer and its impact on clinical applications.

Authors:  Meike Körner; Emanuel Christ; Damian Wild; Jean Claude Reubi
Journal:  Front Endocrinol (Lausanne)       Date:  2012-12-06       Impact factor: 5.555

9.  Glucagon-like peptide-1 receptor imaging with [Lys40(Ahx-HYNIC- 99mTc/EDDA)NH2]-exendin-4 for the detection of insulinoma.

Authors:  Anna Sowa-Staszczak; Dorota Pach; Renata Mikołajczak; Helmut Mäcke; Agata Jabrocka-Hybel; Agnieszka Stefańska; Monika Tomaszuk; Barbara Janota; Aleksandra Gilis-Januszewska; Maciej Małecki; Grzegorz Kamiński; Aldona Kowalska; Jan Kulig; Andrzej Matyja; Czesław Osuch; Alicja Hubalewska-Dydejczyk
Journal:  Eur J Nucl Med Mol Imaging       Date:  2012-12-07       Impact factor: 9.236

  9 in total
  1 in total

Review 1.  Exendin-4 analogs in insulinoma theranostics.

Authors:  Tom J P Jansen; Sanne A M van Lith; Marti Boss; Maarten Brom; Lieke Joosten; Martin Béhé; Mijke Buitinga; Martin Gotthardt
Journal:  J Labelled Comp Radiopharm       Date:  2019-08       Impact factor: 1.921

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.