F U Lang1, K Stegmayer2, T Becker3, M Jäger3. 1. Klinik für Psychiatrie und Psychotherapie II der Universität Ulm, Bezirkskrankenhaus Günzburg, Ludwig-Heilmeyer-Str. 2, 89312, Günzburg, Deutschland. fabian.lang@uni-ulm.de. 2. Universitätsklinik für Psychiatrie und Psychotherapie Bern, Bern, Schweiz. 3. Klinik für Psychiatrie und Psychotherapie II der Universität Ulm, Bezirkskrankenhaus Günzburg, Ludwig-Heilmeyer-Str. 2, 89312, Günzburg, Deutschland.
Abstract
BACKGROUND: In order to reduce heterogeneity in schizophrenia a system-specific approach consisting of the domains 'language', 'affect' and 'motor behavior' was proposed namely the Bern psychopathology scale (BPS). Using the example of the affective domain we examined this system-specific approach for its applicability to clinical practice using a qualitative-casuistic method. Moreover, we examined the possibility to identify a homogeneous subgroup of patients applying this approach. MATERIAL AND METHODS: From a sample of 100 patients with schizophrenia a total of six patients was selected and described following a traditional psychopathological case approach. To expand this qualitative-casuistic method we included the results of standardized psychopathological assessments using the BPS and the positive and negative syndrome scale of schizophrenia (PANSS). RESULTS: Schizophrenic psychoses with affect-dominant symptoms could be characterized better using a system-specific approach than the positive-negative-concept. Ensuing from the cross-sectional psychopathological patterns only limited statements regarding the prospective course were possible. DISCUSSION: The concept of an affect-dominant subtype of schizophrenia was not entirely convincing with respect of the heterogeneous course of the patients described. Nevertheless, the system-specific approach may hold promise for the future regarding further neurobiological research.
BACKGROUND: In order to reduce heterogeneity in schizophrenia a system-specific approach consisting of the domains 'language', 'affect' and 'motor behavior' was proposed namely the Bern psychopathology scale (BPS). Using the example of the affective domain we examined this system-specific approach for its applicability to clinical practice using a qualitative-casuistic method. Moreover, we examined the possibility to identify a homogeneous subgroup of patients applying this approach. MATERIAL AND METHODS: From a sample of 100 patients with schizophrenia a total of six patients was selected and described following a traditional psychopathological case approach. To expand this qualitative-casuistic method we included the results of standardized psychopathological assessments using the BPS and the positive and negative syndrome scale of schizophrenia (PANSS). RESULTS:Schizophrenic psychoses with affect-dominant symptoms could be characterized better using a system-specific approach than the positive-negative-concept. Ensuing from the cross-sectional psychopathological patterns only limited statements regarding the prospective course were possible. DISCUSSION: The concept of an affect-dominant subtype of schizophrenia was not entirely convincing with respect of the heterogeneous course of the patients described. Nevertheless, the system-specific approach may hold promise for the future regarding further neurobiological research.
Authors: Josef Parnas; Paul Møller; Tilo Kircher; Jørgen Thalbitzer; Lennart Jansson; Peter Handest; Dan Zahavi Journal: Psychopathology Date: 2005-09-20 Impact factor: 1.944
Authors: F U Lang; S Walther; K Stegmayer; H Anderson-Schmidt; T G Schulze; T Becker; M Jäger Journal: Compr Psychiatry Date: 2015-06-03 Impact factor: 3.735
Authors: Heike Anderson-Schmidt; Lothar Adler; Chadiga Aly; Ion-George Anghelescu; Michael Bauer; Jessica Baumgärtner; Joachim Becker; Roswitha Bianco; Thomas Becker; Cosima Bitter; Dominikus Bönsch; Karoline Buckow; Monika Budde; Martin Bührig; Jürgen Deckert; Sara Y Demiroglu; Detlef Dietrich; Michael Dümpelmann; Uta Engelhardt; Andreas J Fallgatter; Daniel Feldhaus; Christian Figge; Here Folkerts; Michael Franz; Katrin Gade; Wolfgang Gaebel; Hans-Jörgen Grabe; Oliver Gruber; Verena Gullatz; Linda Gusky; Urs Heilbronner; Krister Helbing; Ulrich Hegerl; Andreas Heinz; Tilman Hensch; Christoph Hiemke; Markus Jäger; Anke Jahn-Brodmann; Georg Juckel; Franz Kandulski; Wolfgang P Kaschka; Tilo Kircher; Manfred Koller; Carsten Konrad; Johannes Kornhuber; Marina Krause; Axel Krug; Mahsa Lee; Markus Leweke; Klaus Lieb; Mechthild Mammes; Andreas Meyer-Lindenberg; Moritz Mühlbacher; Matthias J Müller; Vanessa Nieratschker; Barbara Nierste; Jacqueline Ohle; Andrea Pfennig; Marlenna Pieper; Matthias Quade; Daniela Reich-Erkelenz; Andreas Reif; Markus Reitt; Bernd Reininghaus; Eva Z Reininghaus; Matthias Riemenschneider; Otto Rienhoff; Patrik Roser; Dan Rujescu; Rebecca Schennach; Harald Scherk; Max Schmauss; Frank Schneider; Alexandra Schosser; Björn H Schott; Sybille G Schwab; Jens Schwanke; Daniela Skrowny; Carsten Spitzer; Sebastian Stierl; Judith Stöckel; Susanne Stübner; Andreas Thiel; Hans-Peter Volz; Martin von Hagen; Henrik Walter; Stephanie H Witt; Thomas Wobrock; Jürgen Zielasek; Jörg Zimmermann; Antje Zitzelsberger; Wolfgang Maier; Peter G Falkai; Marcella Rietschel; Thomas G Schulze Journal: Eur Arch Psychiatry Clin Neurosci Date: 2013-04-03 Impact factor: 5.270
Authors: B Pfuhlmann; B Jabs; G Althaus; A Schmidtke; A Bartsch; G Stöber; H Beckmann; E Franzek Journal: J Affect Disord Date: 2004-11-15 Impact factor: 4.839
Authors: Katharina Stegmayer; Helge Horn; Andrea Federspiel; Nadja Razavi; Tobias Bracht; Karin Laimböck; Werner Strik; Thomas Dierks; Roland Wiest; Thomas J Müller; Sebastian Walther Journal: Neuroimage Clin Date: 2013-12-27 Impact factor: 4.881