| Literature DB >> 26646367 |
Amit K Simlandy1, Santanu Mukherjee1.
Abstract
A formal γ-allylation of deconjugated butenolides is reported based on a two-step sequence consisting of a catalytic diastereo- and enantioselective vinylogous nucleophilic addition to vinyl sulfones and Julia-Kocienski olefination. This highly modular approach delivers densely functionalized butenolides containing a quaternary stereogenic centre in excellent yield with high enantioselectivity.Entities:
Year: 2016 PMID： 26646367 DOI： 10.1039/c5ob02362a
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876