Literature DB >> 26645400

Emerging Agents for the Management of Nephrotic Syndrome: Progress to Date.

Keisha L Gibson1, Panupong Hansrivijit2, Maria E Ferris3.   

Abstract

Nephrotic Syndrome is a rare condition associated with high morbidity in the 20-40% of children and adolescents who fail to respond to standard immunosuppressive therapies. Novel non-immunologic mechanisms of widely used immunosuppressive therapies, as well as emerging anti-inflammatory drugs, and anti-fibrotics may play a crucial role in the treatment of patients with refractory disease. This article will review some of these treatments and their various stages of investigation.

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Year:  2016        PMID： 26645400     DOI： 10.1007/s40272-015-0148-y

Source DB:  PubMed          Journal:  Paediatr Drugs        ISSN： 1174-5878            Impact factor:   3.022


  36 in total

Review 1.  The endothelin system and endothelin receptor antagonists.

Authors:  Karin A M Jandeleit-Dahm; Anna M D Watson
Journal:  Curr Opin Nephrol Hypertens       Date:  2012-01       Impact factor: 2.894

Review 2.  Treatment of steroid-sensitive nephrotic syndrome: new guidelines from KDIGO.

Authors:  Rebecca M Lombel; Debbie S Gipson; Elisabeth M Hodson
Journal:  Pediatr Nephrol       Date:  2012-10-03       Impact factor: 3.714

3.  Changing patterns in the histopathology of idiopathic nephrotic syndrome in children.

Authors:  M Bonilla-Felix; C Parra; T Dajani; M Ferris; R D Swinford; R J Portman; R Verani
Journal:  Kidney Int       Date:  1999-05       Impact factor: 10.612

Review 4.  Pirfenidone: in idiopathic pulmonary fibrosis.

Authors:  Natalie J Carter
Journal:  Drugs       Date:  2011-09-10       Impact factor: 9.546

5.  Generation of biologically active linear and cyclic peptides has revealed a unique fine specificity of rituximab and its possible cross-reactivity with acid sphingomyelinase-like phosphodiesterase 3b precursor.

Authors:  Federico Perosa; Elvira Favoino; Maria Antonietta Caragnano; Franco Dammacco
Journal:  Blood       Date:  2005-10-13       Impact factor: 22.113

6.  High incidence of initial and late steroid resistance in childhood nephrotic syndrome.

Authors:  Jung Sue Kim; Christine A Bellew; Douglas M Silverstein; Diego H Aviles; Frank G Boineau; V Matti Vehaskari
Journal:  Kidney Int       Date:  2005-09       Impact factor: 10.612

7.  Pentoxifylline in the treatment of refractory nephrotic syndrome secondary to lupus nephritis.

Authors:  Griselda Galindo-Rodríguez; Reyna Bustamante; Gerardo Esquivel-Nava; Daniel Salazar-Exaire; Jorge Vela-Ojeda; Manuel Vadillo-Buenfil; J Antonio Aviña-Zubieta
Journal:  J Rheumatol       Date:  2003-11       Impact factor: 4.666

8.  Inhibition of tumor necrosis factor and subsequent endotoxin shock by pirfenidone.

Authors:  W C Cain; R W Stuart; D L Lefkowitz; J D Starnes; S Margolin; S S Lefkowitz
Journal:  Int J Immunopharmacol       Date:  1998-12

Review 9.  Pentoxifylline for diabetic kidney disease.

Authors:  Dan Shan; Hong Mei Wu; Qi Yuan Yuan; Jun Li; Rong Le Zhou; Guan J Liu
Journal:  Cochrane Database Syst Rev       Date:  2012-02-15

10.  Rituximab is a safe and effective long-term treatment for children with steroid and calcineurin inhibitor-dependent idiopathic nephrotic syndrome.

Authors:  Pietro Ravani; Alessandro Ponticelli; Chiara Siciliano; Alessia Fornoni; Alberto Magnasco; Felice Sica; Monica Bodria; Gianluca Caridi; Changli Wei; Mirco Belingheri; Luciana Ghio; Sandra Merscher-Gomez; Alberto Edefonti; Andrea Pasini; Giovanni Montini; Corrado Murtas; Xiangyu Wang; Daniel Muruve; Augusto Vaglio; Davide Martorana; Antonello Pani; Francesco Scolari; Jochen Reiser; Gian M Ghiggeri
Journal:  Kidney Int       Date:  2013-06-05       Impact factor: 10.612
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  2 in total

1.  Potential Molecular Mechanisms of Ephedra Herb in the Treatment of Nephrotic Syndrome Based on Network Pharmacology and Molecular Docking.

Authors:  Tianwen Yao; Qingliang Wang; Shisheng Han; Yan Lu; Yanqiu Xu; Yi Wang
Journal:  Biomed Res Int       Date:  2022-07-05       Impact factor: 3.246

Review 2.  Traditional Chinese Medicine for Refractory Nephrotic Syndrome: Strategies and Promising Treatments.

Authors:  Xiao-Qin Wang; Lan Wang; Yuan-Chao Tu; Yuan Clare Zhang
Journal:  Evid Based Complement Alternat Med       Date:  2018-01-04       Impact factor: 2.629
  2 in total

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