| Literature DB >> 26645289 |
I G Agafonova1, R N Bogdanovich2, N G Kolosova3,4.
Abstract
Magnetic resonance tomography was employed to verify endothelial dysfunction of renal arteries in Wistar and OXYS rats under conditions of induced arterial hypertension. Angiography revealed changes in the size and form of renal arteries of hypertensive animals. In hypertensive rats, histochrome exerted a benevolent therapeutic effect in renal arteries: it decreased BP, diminished thrombus formation in fi ne capillaries and arterioles, demonstrated the anticoagulant properties, partially improved endothelial dysfunction of small renal arteries, and up-regulated the glomerular filtration.Entities:
Keywords: OXYS rats; angiography; arterial hypertension; endothelial vasomotor function; magnetic resonance tomography
Mesh:
Substances:
Year: 2015 PMID: 26645289 DOI: 10.1007/s10517-015-3134-z
Source DB: PubMed Journal: Bull Exp Biol Med ISSN: 0007-4888 Impact factor: 0.804