Literature DB >> 2664391

What is the relationship between the endothelium derived relaxant factor and nitric oxide?

C J Long1, B A Berkowitz.   

Abstract

Nitric oxide gas in solution (NO) relaxes blood vessels with similar actions and pharmacodynamics as the endothelium derived relaxant factor (EDRF) and has been proposed to be a component of the materials released from stimulated endothelial cells. Certain data however suggest that EDRF and NO may not be identical. In some non-vascular smooth muscles, NO and EDRF exhibit markedly different pharmacologic profiles. Furthermore the interaction of EDRF and NO with anion exchange resins differ. The hypothesis that EDRF is identical to nitric oxide gas in solution or a nitrogen oxide containing compound is discussed.

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Year:  1989        PMID： 2664391     DOI： 10.1016/0024-3205(89)90429-3

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  9 in total

1.  N-hydroxylamine is not an intermediate in the conversion of L-arginine to an activator of soluble guanylate cyclase in neuroblastoma N1E-115 cells.

Authors:  S Pou; W S Pou; G M Rosen; E E el-Fakahany
Journal:  Biochem J       Date:  1991-02-01       Impact factor: 3.857

2.  Comparison of relaxation responses of vascular and non-vascular smooth muscle to endothelium-derived relaxing factor (EDRF), acidified sodium nitrite (NO) and sodium nitroprusside.

Authors:  T M Cocks; J A Angus
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-04       Impact factor: 3.000

3.  Localization of nitrergic neuronal and non-neuronal cells in the ultimobranchial glands of the chicken.

Authors:  S M Ali; A S Chan; S K Leong
Journal:  Anat Embryol (Berl)       Date:  1996-02

4.  Regional and cardiac haemodynamic responses to glyceryl trinitrate, acetylcholine, bradykinin and endothelin-1 in conscious rats: effects of NG-nitro-L-arginine methyl ester.

Authors:  S M Gardiner; A M Compton; P A Kemp; T Bennett
Journal:  Br J Pharmacol       Date:  1990-11       Impact factor: 8.739

5.  Effects of NG-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, 5'-N-ethylcarboxamidoadenosine or salbutamol in conscious rats.

Authors:  S M Gardiner; P A Kemp; T Bennett
Journal:  Br J Pharmacol       Date:  1991-07       Impact factor: 8.739

6.  Selective impairment of hindquarters vasodilator responses to bradykinin in conscious Wistar rats with streptozotocin-induced diabetes mellitus.

Authors:  R J Kiff; S M Gardiner; A M Compton; T Bennett
Journal:  Br J Pharmacol       Date:  1991-06       Impact factor: 8.739

7.  Distribution and colocalization of nitric oxide synthase and NADPH-diaphorase in adrenal gland of developing, adult and aging Sprague-Dawley rats.

Authors:  M Afework; A Tomlinson; G Burnstock
Journal:  Cell Tissue Res       Date:  1994-04       Impact factor: 5.249

8.  Endothelium-dependent relaxation of rabbit middle cerebral artery to a histamine H3-agonist is reduced by inhibitors of nitric oxide and prostacyclin synthesis.

Authors:  L Ea Kim; J Javellaud; N Oudart
Journal:  Br J Pharmacol       Date:  1992-01       Impact factor: 8.739

9.  Endothelium-dependent relaxation of rat aorta to a histamine H(3) agonist is reduced by inhibitors of nitric oxide synthase, guanylate cyclase and Na,K-ATPase.

Authors:  D M Djuric; M T Nesic; I Z Andjelkovic
Journal:  Mediators Inflamm       Date:  1996       Impact factor: 4.711
  9 in total

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