| Literature DB >> 26642087 |
Emilie C J Syed1,2,3, Laura L Grima3, Peter J Magill2, Rafal Bogacz1,2, Peter Brown1,2, Mark E Walton3.
Abstract
It is widely held that dopamine signaling encodes predictions of future rewards and such predictions are regularly used to drive behavior, but the relationship between these two is poorly defined. We found in rats that nucleus accumbens dopamine following a reward-predicting cue was attenuated unless movement was correctly initiated. Our results indicate that dopamine release in this region is contingent on correct action initiation and not just reward prediction.Entities:
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Year: 2015 PMID： 26642087 PMCID： PMC4697363 DOI： 10.1038/nn.4187
Source DB: PubMed Journal: Nat Neurosci ISSN： 1097-6256 Impact factor: 24.884