Literature DB >> 26640902

Early Infections in Renal Transplant Recipients: Incidence, Risk Factors, and Causative Microorganisms.

Hakan Yabanoğlu1, Hikmet Eda Alışkan, Kenan Çalışkan, İlker Arer, Aydıncan Akdur, Sedat Yıldırım, Gökhan Moray, Mehmet Haberal.   

Abstract

OBJECTIVES: This study aimed to compare renal transplant recipients with and without infection with respect to demographic and clinical characteristics as well as risk factors; to determine the incidence of posttransplant infections; and to study the antibiotic resistance patterns of bacterial species identified as the causative organisms in posttransplant infections.
MATERIALS AND METHODS: This study included a total of 136 patients undergoing renal transplant in a 4-year period. The patients were categorized into 2 groups. The 2 groups were compared with each other with respect to general clinical and demographic variables and the number and frequency of infectious attacks within a 1-year follow-up, infection type, and antibiotic resistance patterns.
RESULTS: Ninety-two (67.6%) of the subjects were male and 44 (32.4%) were female. A total of 57 (41.9%) patients developed 128 infectious attacks. Urinary tract infections were the most common infections (42.1%). There was a significant correlation between a clinically relevant urinary culture proliferation and postoperative infection rate (P = .002). There was a significant correlation between antimicrobial resistance and the number of infectious attacks (P = .023). There was a significant correlation between the proliferation of Extended Spectrum Beta Lactamase-positive Enterobactericeae species and the number of infectious attacks (P = .000).
CONCLUSIONS: Presence of a clinically relevant proliferation in the preoperative urinary culture, which was identified as a risk factor for infection, increased the number of infectious attacks. Moreover, Extended Spectrum Beta Lactamase-positive Enterobactericeae species increased the number of infections. These 2 principle results should be taken into account in patient management.

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Year:  2015        PMID: 26640902     DOI: 10.6002/ect.tdtd2015.O9

Source DB:  PubMed          Journal:  Exp Clin Transplant        ISSN: 1304-0855            Impact factor:   0.945


  3 in total

1.  Evaluation of early and late-term infections after renal transplantation: Clinical experiences of Sanko University Medical Faculty Transplantation Center.

Authors:  Hatem Kazımoğlu; Rezan Harman; Mehmet Necmettin Mercimek; Mehmet Dokur; Erdal Uysal
Journal:  Turk J Urol       Date:  2018-07-27

2.  Epidemiology, susceptibility, and risk factors for acquisition of MDR/XDR Gram-negative bacteria among kidney transplant recipients with urinary tract infections.

Authors:  Xiuhong Yuan; Taohua Liu; Di Wu; Qiquan Wan
Journal:  Infect Drug Resist       Date:  2018-05-14       Impact factor: 4.003

3.  Application of metagenomic next-generation sequencing in the diagnosis and treatment of recurrent urinary tract infection in kidney transplant recipients.

Authors:  Wenjing Duan; Yongguang Yang; Jingge Zhao; Tianzhong Yan; Xiangyong Tian
Journal:  Front Public Health       Date:  2022-08-22
  3 in total

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