Sho Sato1, Kuniya Tanaka2, Kazunori Nojiri1, Takafumi Kumamoto1, Ryutaro Mori1, Kouichi Taniguchi1, Ryusei Matsuyama1, Kazuhisa Takeda1, Michio Ueda1, Hirotoshi Akiyama1, Masataka Taguri3, Itaru Endo4. 1. Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama City, Japan. 2. Department of Surgery, Teikyo University Medical Center, Ichihara City, Japan. 3. Department of Clinical Statistics, Yokohama City University Graduate School of Medicine, Yokohama City, Japan. 4. Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama City, Japan endoit@med.yokohama-cu.ac.jp.
Abstract
BACKGROUND: The number of elderly patients who undergo hepatectomy for hepatocellular carcinoma (HCC) has been increasing. Therefore, criteria for selection of an appropriate hepatectomy procedure are required. PATIENTS AND METHODS: Two hundred and twenty-nine HCC patients undergoing hepatectomy were enrolled in the present study. Patients were classified into two groups: the elderly group (age ≥75 years, n=34) and the non-elderly group (age <75 years, n=195). The hepatectomy procedure was selected based on the prognostic score (PS) formula, that includes patient age as a variable. RESULTS: The incidence of non-anatomical resection was higher (p=0.015) and the weight of resected specimens was lower (p=0.019) in the elderly group than in the non-elderly group. No significant difference was observed in the postoperative complication rate between the two groups. The 5-year survival rates were comparable between the two groups. CONCLUSION: Favorable short- and long-term outcomes can be obtained based on cautious selection criteria for hepatectomy procedures, while considering patient age, in the treatment of elderly patients with HCC. Copyright
BACKGROUND: The number of elderly patients who undergo hepatectomy for hepatocellular carcinoma (HCC) has been increasing. Therefore, criteria for selection of an appropriate hepatectomy procedure are required. PATIENTS AND METHODS: Two hundred and twenty-nine HCCpatients undergoing hepatectomy were enrolled in the present study. Patients were classified into two groups: the elderly group (age ≥75 years, n=34) and the non-elderly group (age <75 years, n=195). The hepatectomy procedure was selected based on the prognostic score (PS) formula, that includes patient age as a variable. RESULTS: The incidence of non-anatomical resection was higher (p=0.015) and the weight of resected specimens was lower (p=0.019) in the elderly group than in the non-elderly group. No significant difference was observed in the postoperative complication rate between the two groups. The 5-year survival rates were comparable between the two groups. CONCLUSION: Favorable short- and long-term outcomes can be obtained based on cautious selection criteria for hepatectomy procedures, while considering patient age, in the treatment of elderly patients with HCC. Copyright