Literature DB >> 2663681

[Comparison of the action of 2 effective analgesics. Experimental study: tramadol versus tilidine/naloxone].

B Bromm, W M Herrmann, E Scharein.   

Abstract

In the present study involving healthy test subjects, tilidin/naloxone (Valoron N; VAL) proved to have an analgesic effect roughly twice as pronounced as that of tramadol (TRA). Moreover, the analgesic effect of VAL showed a significantly more rapid onset than did that of TRA. This finding reflects the difference in rate of action of the active substances. In accordance with these findings, VAL is thus the most powerful analgesic presently available on the German market on simple prescription.

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Year:  1989        PMID: 2663681

Source DB:  PubMed          Journal:  Fortschr Med        ISSN: 0015-8178


  3 in total

1.  [Not Available].

Authors:  B Bromm
Journal:  Schmerz       Date:  1992-03       Impact factor: 1.107

Review 2.  Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states.

Authors:  C R Lee; D McTavish; E M Sorkin
Journal:  Drugs       Date:  1993-08       Impact factor: 9.546

3.  A comparison of the antinociceptive effects of imipramine, tramadol and anpirtoline.

Authors:  T Hummel; C Hummel; I Friedel; E Pauli; G Kobal
Journal:  Br J Clin Pharmacol       Date:  1994-04       Impact factor: 4.335

  3 in total

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