Literature DB >> 26636492

Metastasis and Oxidative Stress: Are Antioxidants a Metabolic Driver of Progression?

Maria Peiris-Pagès1, Ubaldo E Martinez-Outschoorn2, Federica Sotgia1, Michael P Lisanti3.   

Abstract

The role of reactive oxygen species (ROS) and antioxidants in cancer is controversial because of their context-dependent ability to promote or suppress tumorigenesis. Piskounova et al. (2015) now show that ROS limit distant metastasis: only cells with increased antioxidant capacity are able to succeed in their purpose to metastasize.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26636492     DOI: 10.1016/j.cmet.2015.11.008

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  33 in total

Review 1.  p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.

Authors:  Koji Taniguchi; Shinichiro Yamachika; Feng He; Michael Karin
Journal:  FEBS Lett       Date:  2016-08-06       Impact factor: 4.124

Review 2.  Autophagy: In the cROSshairs of cancer.

Authors:  Heather Graham Hambright; Rita Ghosh
Journal:  Biochem Pharmacol       Date:  2016-10-24       Impact factor: 5.858

3.  Monocarboxylate Transporter 4 in Cancer-Associated Fibroblasts Is a Driver of Aggressiveness in Aerodigestive Tract Cancers.

Authors:  Marina Domingo-Vidal; Diana Whitaker-Menezes; Mehri Mollaee; Zhao Lin; Madalina Tuluc; Nancy Philp; Jennifer M Johnson; Tingting Zhan; Joseph Curry; Ubaldo Martinez-Outschoorn
Journal:  Front Oncol       Date:  2022-06-22       Impact factor: 5.738

4.  Multiomics Integration Reveals the Landscape of Prometastasis Metabolism in Hepatocellular Carcinoma.

Authors:  Yongmei Li; Hao Zhuang; Xinran Zhang; Yuan Li; Yun Liu; Xianfu Yi; Guoxuan Qin; Wen Wei; Ruibing Chen
Journal:  Mol Cell Proteomics       Date:  2018-01-25       Impact factor: 5.911

Review 5.  Cancer metabolism: a therapeutic perspective.

Authors:  Ubaldo E Martinez-Outschoorn; Maria Peiris-Pagés; Richard G Pestell; Federica Sotgia; Michael P Lisanti
Journal:  Nat Rev Clin Oncol       Date:  2016-05-04       Impact factor: 66.675

Review 6.  NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential.

Authors:  Na Xie; Lu Zhang; Wei Gao; Canhua Huang; Peter Ernst Huber; Xiaobo Zhou; Changlong Li; Guobo Shen; Bingwen Zou
Journal:  Signal Transduct Target Ther       Date:  2020-10-07

7.  Pilot study demonstrating metabolic and anti-proliferative effects of in vivo anti-oxidant supplementation with N-Acetylcysteine in Breast Cancer.

Authors:  Daniel Monti; Federica Sotgia; Diana Whitaker-Menezes; Madalina Tuluc; Ruth Birbe; Adam Berger; Melissa Lazar; Paolo Cotzia; Rossitza Draganova-Tacheva; Zhao Lin; Marina Domingo-Vidal; Andrew Newberg; Michael P Lisanti; Ubaldo Martinez-Outschoorn
Journal:  Semin Oncol       Date:  2017-10-10       Impact factor: 4.929

8.  PIAS3/SOCS1-STAT3 axis responses to oxidative stress in hepatocellular cancer cells.

Authors:  Honghua Sun; Yanglong Li; Xianglan Quan; Ning Chen; Xinglin Jin; Wenbiao Jin; Yongmin Jin; Xionghu Shen
Journal:  Am J Transl Res       Date:  2021-11-15       Impact factor: 4.060

9.  Regulation of redox balance using a biocompatible nanoplatform enhances phototherapy efficacy and suppresses tumor metastasis.

Authors:  Qunying Jiang; Min Pan; Jialing Hu; Junlin Sun; Lei Fan; Zhiqiao Zou; Jianshuang Wei; Xiaoquan Yang; Xiaoqing Liu
Journal:  Chem Sci       Date:  2020-10-22       Impact factor: 9.825

10.  Key Role of MCUR1 in Malignant Progression of Breast Cancer.

Authors:  Peipei Gao; Ting Peng; Shitong Lin; Wenhua Zhi; Canhui Cao; Ping Wu; Ling Xi; Peng Wu; Qin Yang; Wencheng Ding
Journal:  Onco Targets Ther       Date:  2021-07-13       Impact factor: 4.147

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