Literature DB >> 2663636

Complete nucleotide sequence of immunogenic protein MPB70 from Mycobacterium bovis BCG.

K Terasaka1, R Yamaguchi, K Matsuo, A Yamazaki, S Nagai, T Yamada.   

Abstract

The extracellular protein MPB70 is a heat-stable immunogenic protein which was found in the culture filtrate of Mycobacterium bovis BCG Japanese. We determined the complete nt and aa sequences of MPB70 and correlated with the previously reported data. The N-terminal sequence revealed that the signal peptide (SP) consisted of 30 aa and that the mature protein had 163 aa with a molecular weight of 16,305. The SP displayed a characteristic feature of an Ala-rich property which would be efficient in a SP function.

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Year:  1989        PMID： 2663636     DOI： 10.1016/0378-1097(89)90052-9

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  23 in total

1.  Establishment of a foreign antigen secretion system in mycobacteria.

Authors:  K Matsuo; R Yamaguchi; A Yamazaki; H Tasaka; K Terasaka; M Totsuka; K Kobayashi; H Yukitake; T Yamada
Journal:  Infect Immun       Date:  1990-12       Impact factor: 3.441

2.  Cloning and expression of the gene for the cross-reactive alpha antigen of Mycobacterium kansasii.

Authors:  K Matsuo; R Yamaguchi; A Yamazaki; H Tasaka; K Terasaka; T Yamada
Journal:  Infect Immun       Date:  1990-02       Impact factor: 3.441

3.  Modification of the Mycobacterium bovis extracellular protein MPB70 with fluorescein for rapid detection of specific serum antibodies by fluorescence polarization.

Authors:  M Lin; E A Sugden; M E Jolley; K Stilwell
Journal:  Clin Diagn Lab Immunol       Date:  1996-07

4.  Protein G-based enzyme-linked immunosorbent assay for anti-MPB70 antibodies in bovine tuberculosis.

Authors:  M Harboe; H G Wiker; J R Duncan; M M Garcia; T W Dukes; B W Brooks; C Turcotte; S Nagai
Journal:  J Clin Microbiol       Date:  1990-05       Impact factor: 5.948

5.  Pathways for utilization of carbon reserves in Desulfovibrio gigas under fermentative and respiratory conditions.

Authors:  P Fareleira; J Legall; A V Xavier; H Santos
Journal:  J Bacteriol       Date:  1997-06       Impact factor: 3.490

6.  Secretion of the mycobacterial 19-kilodalton protein by Escherichia coli, a novel method for the purification of recombinant mycobacterial antigens.

Authors:  R G Hewinson; D P Harris; A Whelan; W P Russell
Journal:  Clin Diagn Lab Immunol       Date:  1996-01

7.  Evidence for absence of the MPB64 gene in some substrains of Mycobacterium bovis BCG.

Authors:  H Li; J C Ulstrup; T O Jonassen; K Melby; S Nagai; M Harboe
Journal:  Infect Immun       Date:  1993-05       Impact factor: 3.441

8.  Recombinant Mycobacterium bovis BCG secreting functional interleukin-2 enhances gamma interferon production by splenocytes.

Authors:  M A O'Donnell; A Aldovini; R B Duda; H Yang; A Szilvasi; R A Young; W C DeWolf
Journal:  Infect Immun       Date:  1994-06       Impact factor: 3.441

9.  Purification and characterization of major antigens from a Mycobacterium bovis culture filtrate.

Authors:  T Fifis; C Costopoulos; A J Radford; A Bacic; P R Wood
Journal:  Infect Immun       Date:  1991-03       Impact factor: 3.441

10.  Periostin-like-factor and Periostin in an animal model of work-related musculoskeletal disorder.

Authors:  Shobha Rani; Mary F Barbe; Ann E Barr; Judith Litvin
Journal:  Bone       Date:  2008-11-27       Impact factor: 4.398
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