Literature DB >> 26634859

Effects of Two Different Dosages of Sildenafil on Patients With Erectile Dysfunction.

Hongjun Li1, Gang Bai1, Xinyu Zhang1, Bingbing Shi1, Defeng Liu2, Hui Jiang2, Zhigang Ji1, Matthew R Davis3, Ziwen Zhu4, Yujiang Fang3,4.   

Abstract

To investigate the effects of two different dosages of sildenafil on patients with erectile dysfunction (ED), a total of 3,674 patients with ED were recruited to answer questionnaires designed specifically for this study. There were 977 patients in the 50 mg group and there were 2,697 patients in the 100 mg group. Both 50 mg and 100 mg of sildenafil therapy increased the ED patients' average monthly frequency of sexual intercourse, improved erectile function state in self-assessment, and elevated sexual satisfaction and enjoyment. Despite a higher rate of concomitant diseases, patients in the higher dosage of sildenafil group had a better outcome in the average monthly frequency of sexual intercourse and sexual enjoyment compared with those in the lower dosage. Such a study might be helpful for health care providers to choose sildenafil dosage for patients with ED.

Entities:  

Keywords:  dose; erectile dysfunction; sildenafil; therapeutic effect

Mesh:

Substances:

Year:  2015        PMID: 26634859      PMCID: PMC5675238          DOI: 10.1177/1557988315620467

Source DB:  PubMed          Journal:  Am J Mens Health        ISSN: 1557-9883


  14 in total

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Journal:  N Engl J Med       Date:  1998-05-14       Impact factor: 91.245

Review 2.  Oral phosphodiesterase-5 inhibitors and hormonal treatments for erectile dysfunction: a systematic review and meta-analysis.

Authors:  Alexander Tsertsvadze; Howard A Fink; Fatemeh Yazdi; Roderick MacDonald; Anthony J Bella; Mohammed T Ansari; Chantelle Garritty; Karla Soares-Weiser; Raymond Daniel; Margaret Sampson; Steven Fox; David Moher; Timothy J Wilt
Journal:  Ann Intern Med       Date:  2009-11-03       Impact factor: 25.391

Review 3.  Sexual function of the ageing male.

Authors:  Giovanni Corona; Giulia Rastrelli; Elisa Maseroli; Gianni Forti; Mario Maggi
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2013-06-20       Impact factor: 4.690

4.  Sildenafil citrate (Viagra) is effective and well tolerated for treating erectile dysfunction of psychogenic or mixed aetiology.

Authors:  A M Olsson; M J Speakman; W W Dinsmore; F Giuliano; C Gingell; M Maytom; M D Smith; I Osterloh
Journal:  Int J Clin Pract       Date:  2000-11       Impact factor: 2.503

5.  Erectile function, erection hardness and tolerability in men treated with sildenafil 100 mg vs. 50 mg for erectile dysfunction.

Authors:  M Kirby; D L Creanga; V J Stecher
Journal:  Int J Clin Pract       Date:  2013-10       Impact factor: 2.503

6.  Effect of sildenafil on platelet function and platelet cGMP of patients with erectile dysfunction.

Authors:  M Akand; E Gencer; Ö Yaman; G Erişgen; D Tekin; E Özdiler
Journal:  Andrologia       Date:  2014-12-08       Impact factor: 2.775

Review 7.  Erectile dysfunction in diabetes mellitus.

Authors:  Lasantha S Malavige; Jonathan C Levy
Journal:  J Sex Med       Date:  2009-02-10       Impact factor: 3.802

Review 8.  Significance of nitric oxide and its modulation mechanisms by endogenous nitric oxide synthase inhibitors and arginase in the micturition disorders and erectile dysfunction.

Authors:  Hitoshi Masuda
Journal:  Int J Urol       Date:  2008-02       Impact factor: 3.369

Review 9.  Sexual dysfunction and cardiovascular diseases: a systematic review of prevalence.

Authors:  Elisabete Rodrigues Nascimento; Ana Claudia Ornelas Maia; Valeska Pereira; Gastão Soares-Filho; Antonio Egidio Nardi; Adriana Cardoso Silva
Journal:  Clinics (Sao Paulo)       Date:  2013-11       Impact factor: 2.365

Review 10.  Erectile dysfunction in the elderly: an old widespread issue with novel treatment perspectives.

Authors:  Pietro Gareri; Alberto Castagna; Davide Francomano; Gregorio Cerminara; Pasquale De Fazio
Journal:  Int J Endocrinol       Date:  2014-03-17       Impact factor: 3.257

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  1 in total

1.  Relationship between Response to PDE5 Inhibitors and Penile Duplex Doppler Ultrasound in Erectile Dysfunction.

Authors:  Ercan Ogreden; Ural Oğuz; Erhan Demirelli; Alptekin Tosun; Orhan Yalçın
Journal:  Med Sci (Basel)       Date:  2018-03-26
  1 in total

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