Literature DB >> 26633727

Echinacea purpurea: A Proprietary Extract of Echinacea purpurea Is Shown to be Safe and Effective in the Prevention of the Common Cold.

Stephanie Maxine Ross1.   

Abstract

The research study in this review represents the largest clinical trial to date that evaluated the safety and efficacy of Echinacea purpurea for prophylactic treatment of the common cold, in addition to investigating its risk-benefit in a long-term treatment period. The clinical application of the proprietary standardized Echinacea purpurea extract(Echinaforce) demonstrated efficacy as a preventive cold treatment option over a 4-month duration. This study showed that Echinacea’s long-term prevention was associated with a reduction in the total number of cold episodes, a reduction in the number of days with colds, and a reduction in cold episodes requiring additional medication. Furthermore, the Echinacea test agent inhibited virally confirmed colds, exhibited maximal effects on recurrent infections, and demonstrated that its preventive effects increased relative to therapy compliance and adherence to the protocol. In summary, Echinacea purpurea when taken as recommended for the prevention of the common cold appears to provide a positive risk to benefit ratio.

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Year:  2016        PMID: 26633727     DOI: 10.1097/HNP.0000000000000130

Source DB:  PubMed          Journal:  Holist Nurs Pract        ISSN: 0887-9311            Impact factor:   1.000


  5 in total

1.  Echinacea angustifolia and Echinacea purpurea Supplementation Combined with Vaginal Hyaluronic Acid to Boost the Remission of Cervical Low-Grade Squamous Intraepithelial Lesions (L-SILs): A Randomized Controlled Trial.

Authors:  Gaetano Riemma; Maria Teresa Schettino; Gaetano Maria Munno; Diego Domenico Fasulo; Lucia Sandullo; Emanuele Amabile; Marco La Verde; Marco Torella
Journal:  Medicina (Kaunas)       Date:  2022-05-09       Impact factor: 2.948

2.  Echinacoside Increases Sperm Quantity in Rats by Targeting the Hypothalamic Androgen Receptor.

Authors:  Zhihui Jiang; Bo Zhou; Xinping Li; Gordon M Kirby; Xiaoying Zhang
Journal:  Sci Rep       Date:  2018-03-01       Impact factor: 4.379

Review 3.  Can Echinacea be a potential candidate to target immunity, inflammation, and infection - The trinity of coronavirus disease 2019.

Authors:  M F Nagoor Meeran; Hayate Javed; Charu Sharma; Sameer N Goyal; Sanjay Kumar; Niraj Kumar Jha; Shreesh Ojha
Journal:  Heliyon       Date:  2021-02-08

4.  Application of HPLC Fingerprint Combined with Chemical Pattern Recognition and Multi-Component Determination in Quality Evaluation of Echinacea purpurea (L.) Moench.

Authors:  Xuzhen Lv; Shuai Feng; Jiacheng Zhang; Sihai Sun; Yannan Geng; Min Yang; Yali Liu; Lu Qin; Tianlun Zhao; Chenxi Wang; Guangxu Liu; Feng Li
Journal:  Molecules       Date:  2022-09-30       Impact factor: 4.927

5.  Simultaneous Determination of Seven Phenolic Acids in Rat Plasma Using UHPLC-ESI-MS/MS after Oral Administration of Echinacea purpurea Extract.

Authors:  Yan Du; Zhibin Wang; Libo Wang; Mingjie Gao; Liqian Wang; Chunli Gan; Chunjuan Yang
Journal:  Molecules       Date:  2017-09-07       Impact factor: 4.411

  5 in total

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