Literature DB >> 26633567

Overexpression of AtPTPA in Arabidopsis increases protein phosphatase 2A activity by promoting holoenzyme formation and ABA negatively affects holoenzyme formation.

Jian Chen1, Xunlu Zhu1, Guoxin Shen2, Hong Zhang1.   

Abstract

AtPTPA is a critical regulator for the holoenzyme assembling of protein phosphatase 2A (PP2A) in Arabidopsis. Characterization of AtPTPA improves our understanding of the function and regulation of PP2A in eukaryotes. Further analysis of AtPTPA-overexpressing plants indicates that AtPTPA increases PP2A activity by promoting PP2A's AC dimer formation, thereby holoenzyme assembling. Plant hormone abscisic acid (ABA) reduces PP2A enzyme activity by negatively affects PP2A's AC dimer formation. Therefore, AtPTPA is a positive factor that promotes PP2A holoenzyme assembly, and ABA is a negative factor that prevents PP2A holoenzyme assembly.

Entities:  

Keywords:  Arabidopsis; PP2A holoenzyme assembly; PP2Ac methylation; protein phosphatase 2A

Mesh：

Substances：

Year:  2015        PMID： 26633567      PMCID： PMC4883891          DOI： 10.1080/15592324.2015.1052926

Source DB:  PubMed          Journal:  Plant Signal Behav        ISSN： 1559-2316


  13 in total

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Authors:  Thomas Fellner; Daniel H Lackner; Hans Hombauer; Patrick Piribauer; Ingrid Mudrak; Katrin Zaragoza; Claudia Juno; Egon Ogris
Journal:  Genes Dev       Date:  2003-09-01       Impact factor: 11.361

2.  Disruption of a guard cell-expressed protein phosphatase 2A regulatory subunit, RCN1, confers abscisic acid insensitivity in Arabidopsis.

Authors:  June M Kwak; Ji-Hye Moon; Yoshiyuki Murata; Kazuyuki Kuchitsu; Nathalie Leonhardt; Alison DeLong; Julian I Schroeder
Journal:  Plant Cell       Date:  2002-11       Impact factor: 11.277

3.  TAP46 plays a positive role in the ABSCISIC ACID INSENSITIVE5-regulated gene expression in Arabidopsis.

Authors:  Rongbin Hu; Yinfeng Zhu; Guoxin Shen; Hong Zhang
Journal:  Plant Physiol       Date:  2013-12-19       Impact factor: 8.340

Review 4.  Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling.

Authors:  V Janssens; J Goris
Journal:  Biochem J       Date:  2001-02-01       Impact factor: 3.857

5.  A mutation in protein phosphatase 2A regulatory subunit A affects auxin transport in Arabidopsis.

Authors:  C Garbers; A DeLong; J Deruére; P Bernasconi; D Söll
Journal:  EMBO J       Date:  1996-05-01       Impact factor: 11.598

6.  The Arabidopsis eer1 mutant has enhanced ethylene responses in the hypocotyl and stem.

Authors:  P B Larsen; C Chang
Journal:  Plant Physiol       Date:  2001-02       Impact factor: 8.340

7.  A protein phosphatase 2A catalytic subunit is a negative regulator of abscisic acid signalling.

Authors:  Mónica Pernas; Gloria García-Casado; Enrique Rojo; Roberto Solano; Jose J Sánchez-Serrano
Journal:  Plant J       Date:  2007-07-07       Impact factor: 6.417

8.  Antagonistic regulation of PIN phosphorylation by PP2A and PINOID directs auxin flux.

Authors:  Marta Michniewicz; Marcelo K Zago; Lindy Abas; Dolf Weijers; Alois Schweighofer; Irute Meskiene; Marcus G Heisler; Carolyn Ohno; Jing Zhang; Fang Huang; Rebecca Schwab; Detlef Weigel; Elliot M Meyerowitz; Christian Luschnig; Remko Offringa; Jirí Friml
Journal:  Cell       Date:  2007-09-21       Impact factor: 41.582

9.  Protein phosphatase 2A controls ethylene biosynthesis by differentially regulating the turnover of ACC synthase isoforms.

Authors:  Kyle R Skottke; Gyeong Mee Yoon; Joseph J Kieber; Alison DeLong
Journal:  PLoS Genet       Date:  2011-04-21       Impact factor: 5.917

10.  Structural basis of protein phosphatase 2A stable latency.

Authors:  Li Jiang; Vitali Stanevich; Kenneth A Satyshur; Mei Kong; Guy R Watkins; Brian E Wadzinski; Rituparna Sengupta; Yongna Xing
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919
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  1 in total

1.  Root Growth Adaptation is Mediated by PYLs ABA Receptor-PP2A Protein Phosphatase Complex.

Authors:  Yang Li; Yaping Wang; Shutang Tan; Zhen Li; Zhi Yuan; Matouš Glanc; David Domjan; Kai Wang; Wei Xuan; Yan Guo; Zhizhong Gong; Jiří Friml; Jing Zhang
Journal:  Adv Sci (Weinh)       Date:  2019-12-11       Impact factor: 16.806
  1 in total

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