Literature DB >> 26633028

New Glabretal Triterpenes from the Immature Fruits of Poncirus trifoliata and Their Selective Cytotoxicity.

Ae-Ran Choi1, In-Kyoung Lee, E-Eum Woo, Jin-Won Kwon, Bong-Sik Yun, Hae-Ryong Park.   

Abstract

Two new glabretal triterpenes, pancastatins A (1) and B (2), were isolated from the immature fruits of Poncirus trifoliata. Their chemical structures were elucidated by spectroscopic analyses including one- and two-dimensional NMR and high-resolution electrospray ionization mass spectrometry. Compounds 1 and 2 exhibited selective cytotoxicity against PANC-1 pancreatic cancer cells under low-glucose stress conditions.

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Year:  2015        PMID: 26633028     DOI: 10.1248/cpb.c15-00465

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  2 in total

Review 1.  Antitumor Profile of Carbon-Bridged Steroids (CBS) and Triterpenoids.

Authors:  Valery M Dembitsky; Tatyana A Gloriozova; Vladimir V Poroikov
Journal:  Mar Drugs       Date:  2021-06-03       Impact factor: 5.118

2.  Anticancer effects of Poncirus fructus on hepatocellular carcinoma through regulation of apoptosis, migration, and invasion.

Authors:  Suvesh Munakarmi; Lokendra Chand; Hyun Beak Shin; Usama Khamis Hussein; Bong-Sik Yun; Hae Ryong Park; Yeon Jun Jeong
Journal:  Oncol Rep       Date:  2020-10-05       Impact factor: 3.906

  2 in total

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