Literature DB >> 26632795

IgM ocular cicatricial pemphigoid: a unique insight into the immune system.

Noor Tazudeen1, Sonoa Au, Jonathan Pewitt, Elmer Tu, Iris K Aronson.   

Abstract

A 42-year-old man with ocular erythema and scarring had a conjunctival biopsy revealing depostion of IgM and C3 without IgG at the epithelial basement membrane zone.  Treatment with doxycyline, dapsone, and mycophenolate mofetil was unsuccessful and treatment with rituximab has led to partial remission of the conjunctival inflammation. He has undergone 4 cycles of rituximab treatment at intervals of 12 to 18 months.

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Year:  2015        PMID: 26632795

Source DB:  PubMed          Journal:  Dermatol Online J        ISSN: 1087-2108


  3 in total

Review 1.  BP180 Is Critical in the Autoimmunity of Bullous Pemphigoid.

Authors:  Yale Liu; Liang Li; Yumin Xia
Journal:  Front Immunol       Date:  2017-12-08       Impact factor: 7.561

2.  Immunoglobulin M bullous pemphigoid: An enigma.

Authors:  Rosalie Baardman; Barbara Horváth; Maria C Bolling; Hendri H Pas; Gilles F H Diercks
Journal:  JAAD Case Rep       Date:  2020-04-21

Review 3.  Off-Label Uses of Rituximab in Dermatology.

Authors:  Connor Cole; Kyle T Amber
Journal:  Curr Dermatol Rep       Date:  2022-10-06
  3 in total

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