Literature DB >> 26632355

CRISPR Critters and CRISPR Cracks.

R Alta Charo1, Henry T Greely2.   

Abstract

This essay focuses on possible nonhuman applications of CRISPR/Cas9 that are likely to be widely overlooked because they are unexpected and, in some cases, perhaps even "frivolous." We look at five uses for "CRISPR Critters": wild de-extinction, domestic de-extinction, personal whim, art, and novel forms of disease prevention. We then discuss the current regulatory framework and its possible limitations in those contexts. We end with questions about some deeper issues raised by the increased human control over life on earth offered by genome editing.

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Year:  2015        PMID: 26632355     DOI: 10.1080/15265161.2015.1104138

Source DB:  PubMed          Journal:  Am J Bioeth        ISSN: 1526-5161            Impact factor:   11.229


  6 in total

1.  The ethics of genome editing in non-human animals: a systematic review of reasons reported in the academic literature.

Authors:  Nienke de Graeff; Karin R Jongsma; Josephine Johnston; Sarah Hartley; Annelien L Bredenoord
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2019-05-13       Impact factor: 6.237

2.  Governance: Learn from DIY biologists.

Authors:  Todd Kuiken
Journal:  Nature       Date:  2016-03-10       Impact factor: 49.962

3.  CRISPR as a driving force: the Model T of biotechnology.

Authors:  Carlos Mariscal; Angel Petropanagos
Journal:  Monash Bioeth Rev       Date:  2016-06

4.  Ethical principles for the use of human cellular biotechnologies.

Authors:  Paul Root Wolpe; Karen S Rommelfanger
Journal:  Nat Biotechnol       Date:  2017-11-09       Impact factor: 54.908

Review 5.  Emerging ethical perspectives in the clustered regularly interspaced short palindromic repeats genome-editing debate.

Authors:  Silvia Camporesi; Giulia Cavaliere
Journal:  Per Med       Date:  2016-10-28       Impact factor: 2.512

Review 6.  Gene drives in our future: challenges of and opportunities for using a self-sustaining technology in pest and vector management.

Authors:  James P Collins
Journal:  BMC Proc       Date:  2018-07-19
  6 in total

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