Literature DB >> 2663184

The Saccharomyces cerevisiae RAD2 gene complements a Schizosaccharomyces pombe repair mutation.

S J McCready1, H Burkill, S Evans, B S Cox.   

Abstract

Two Saccharomyces cerevisiae genes necessary for excision repair of UV damage in DNA, RAD1 and RAD2, were introduced individually, on a yeast shuttle vector, into seven Schizosaccharomyces pombe mutants - rads 1, 2, 5, 13, 15, 16 and 17. The presence of the cloned RAD1 gene did not affect survival of any of the S. pombe mutants. The RAD2 gene increased survival of S. pombe rad13 to near the wild-type level after UV irradiation and had no effect on any of the other mutants tested. S. pombe rad13 mutants are somewhat defective in removal of pyrimidine dimers so complementation by the S. cerevisiae RAD2 gene suggests that the genes may code for equivalent proteins in the two yeasts.

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Year:  1989        PMID： 2663184     DOI： 10.1007/bf00445748

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  19 in total

1.  Overexpression of the RAD2 gene of S. cerevisiae: identification and preliminary characterization of Rad2 protein.

Authors:  C M Nicolet; E C Friedberg
Journal:  Yeast       Date:  1987-09       Impact factor: 3.239

2.  Repair of pyrimidine dimers in radiation-sensitive mutants rad3, rad4, rad6 and rad9 of Saccharomyces cerevisiae.

Authors:  L Prakash
Journal:  Mutat Res       Date:  1977-10       Impact factor: 2.433

3.  Relation between repair mechanisms and induced mitotic recombination after UV irradiation, in the yeast Schizosaccharomyces pombe. Effects of caffeine.

Authors:  F Fabre
Journal:  Mol Gen Genet       Date:  1972

Review 4.  Recovery, repair, and mutagenesis in Schizosaccharomyces pombe.

Authors:  J Phipps; A Nasim; D R Miller
Journal:  Adv Genet       Date:  1985       Impact factor: 1.944

5.  Synergistic interaction between UV and ionizing radiation in wild-type Schizosaccharomyces pombe.

Authors:  N E Gentner; M M Werner
Journal:  Mol Gen Genet       Date:  1978-08-04

6.  The excision of pyrimidine dimers from DNA of ultraviolet irradiated yeast.

Authors:  P Unrau; R Wheatcroft; B S Cox
Journal:  Mol Gen Genet       Date:  1971

7.  Replicating plasmids in Schizosaccharomyces pombe: improvement of symmetric segregation by a new genetic element.

Authors:  W D Heyer; M Sipiczki; J Kohli
Journal:  Mol Cell Biol       Date:  1986-01       Impact factor: 4.272

8.  Isolation and characterization of the RAD3 gene of Saccharomyces cerevisiae and inviability of rad3 deletion mutants.

Authors:  D R Higgins; S Prakash; P Reynolds; R Polakowska; S Weber; L Prakash
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

9.  Defective thymine dimer excision in radiation-sensitive mutants rad10 and rad16 of Saccharomyces cerevisiae.

Authors:  L Prakash
Journal:  Mol Gen Genet       Date:  1977-04-29

10.  A DNA repair gene required for the incision of damaged DNA is essential for viability in Saccharomyces cerevisiae.

Authors:  L Naumovski; E C Friedberg
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205
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  8 in total

1.  Molecular cloning and analysis of Schizosaccharomyces pombe rad9, a gene involved in DNA repair and mutagenesis.

Authors:  H B Lieberman; K M Hopkins; M Laverty; H M Chu
Journal:  Mol Gen Genet       Date:  1992-04

2.  The Schizosaccharomyces pombe rad3 checkpoint gene.

Authors:  N J Bentley; D A Holtzman; G Flaggs; K S Keegan; A DeMaggio; J C Ford; M Hoekstra; A M Carr
Journal:  EMBO J       Date:  1996-12-02       Impact factor: 11.598

3.  Cloning and analysis of a gene involved in DNA repair and recombination, the rad1 gene of Schizosaccharomyces pombe.

Authors:  P Sunnerhagen; B L Seaton; A Nasim; S Subramani
Journal:  Mol Cell Biol       Date:  1990-07       Impact factor: 4.272

4.  Evolutionary conservation of excision repair in Schizosaccharomyces pombe: evidence for a family of sequences related to the Saccharomyces cerevisiae RAD2 gene.

Authors:  A M Carr; K S Sheldrick; J M Murray; R al-Harithy; F Z Watts; A R Lehmann
Journal:  Nucleic Acids Res       Date:  1993-03-25       Impact factor: 16.971

5.  Human ERCC5 cDNA-cosmid complementation for excision repair and bipartite amino acid domains conserved with RAD proteins of Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Authors:  M A MacInnes; J A Dickson; R R Hernandez; D Learmonth; G Y Lin; J S Mudgett; M S Park; S Schauer; R J Reynolds; G F Strniste
Journal:  Mol Cell Biol       Date:  1993-10       Impact factor: 4.272

6.  The rad16 gene of Schizosaccharomyces pombe: a homolog of the RAD1 gene of Saccharomyces cerevisiae.

Authors:  A M Carr; H Schmidt; S Kirchhoff; W J Muriel; K S Sheldrick; D J Griffiths; C N Basmacioglu; S Subramani; M Clegg; A Nasim
Journal:  Mol Cell Biol       Date:  1994-03       Impact factor: 4.272

Review 7.  DNA Repair in Haploid Context.

Authors:  Loïs Mourrain; Guylain Boissonneault
Journal:  Int J Mol Sci       Date:  2021-11-17       Impact factor: 5.923

8.  Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins.

Authors:  D J Griffiths; N C Barbet; S McCready; A R Lehmann; A M Carr
Journal:  EMBO J       Date:  1995-12-01       Impact factor: 11.598
  8 in total

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