Literature DB >> 26631432

Human Disease Insight: An integrated knowledge-based platform for disease-gene-drug information.

Munazzah Tasleem1, Romana Ishrat1, Asimul Islam1, Faizan Ahmad1, Md Imtaiyaz Hassan2.   

Abstract

The scope of the Human Disease Insight (HDI) database is not limited to researchers or physicians as it also provides basic information to non-professionals and creates disease awareness, thereby reducing the chances of patient suffering due to ignorance. HDI is a knowledge-based resource providing information on human diseases to both scientists and the general public. Here, our mission is to provide a comprehensive human disease database containing most of the available useful information, with extensive cross-referencing. HDI is a knowledge management system that acts as a central hub to access information about human diseases and associated drugs and genes. In addition, HDI contains well-classified bioinformatics tools with helpful descriptions. These integrated bioinformatics tools enable researchers to annotate disease-specific genes and perform protein analysis, search for biomarkers and identify potential vaccine candidates. Eventually, these tools will facilitate the analysis of disease-associated data. The HDI provides two types of search capabilities and includes provisions for downloading, uploading and searching disease/gene/drug-related information. The logistical design of the HDI allows for regular updating. The database is designed to work best with Mozilla Firefox and Google Chrome and is freely accessible at http://humandiseaseinsight.com.
Copyright © 2015 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Data integration; Human disease database; Human genome project; Knowledge management system; Relational database management system

Mesh:

Year:  2015        PMID: 26631432     DOI: 10.1016/j.jiph.2015.10.018

Source DB:  PubMed          Journal:  J Infect Public Health        ISSN: 1876-0341            Impact factor:   3.718


  2 in total

1.  Cruxome: a powerful tool for annotating, interpreting and reporting genetic variants.

Authors:  Qingmei Han; Ying Yang; Shengyang Wu; Yingchun Liao; Shuang Zhang; Hongbin Liang; David S Cram; Yu Zhang
Journal:  BMC Genomics       Date:  2021-06-03       Impact factor: 3.969

2.  Application of median lethal concentration (LC50) of pathogenic microorganisms and their antigens in vaccine development.

Authors:  Saganuwan Alhaji Saganuwan
Journal:  BMC Res Notes       Date:  2020-06-15
  2 in total

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