Alessandro Mantovani1, Andrea Giani2, Carl P Herbort3, Giovanni Staurenghi4. 1. Ophthalmology Unit, Ospedale Valduce, Como, Italy. 2. Eye Clinic Department of Clinical Science "Luigi Sacco", Luigi Sacco Hospital University of Milan, via G.B. Grassi, 74 - 20157, Milan, Italy. 3. Retinal and Inflammatory Eye Diseases, Centre for Ophthalmic Specialised Care & University of Lausanne, Lausanne, Switzerland. 4. Eye Clinic Department of Clinical Science "Luigi Sacco", Luigi Sacco Hospital University of Milan, via G.B. Grassi, 74 - 20157, Milan, Italy. giovanni.staurenghi@unimi.it.
Abstract
PURPOSE: We aimed to describe imaging findings in primary inflammatory choriocapillaropathies (PICCPs) after a photobleaching process. METHODS: 2Images from six consecutive cases of patients affected by PICCPs (four with multiple evanescent white dot syndrome and two with multifocal choroiditis) were reviewed. Patients underwent fundus autofluorescence (FAF), fluorescein angiography (FA), indocyanine green angiography (ICGA), and spectral-domain optical coherence tomography (SD-OCT) by means of the Spectralis HRA (Heidelberg Engineering, Heidelberg, Germany). FAF images were acquired at the beginning of the examination in partially dark-adapted conditions followed by light adapted conditions. RESULTS: During the active phase of the diseases, all patients showed areas of increased FAF that became isoautofluorescent after photobleaching. Simultaneously with increased FAF, the ICGA showed typical hypofluorescent dark areas that were more evident in the late phase. SD-OCT showed disruptions in the hyper-reflective band at the ellipsoid zone. CONCLUSIONS: FAF and SD-OCT are complementary imaging techniques that show alterations in the outer retina of patients affected by PICCPs.
PURPOSE: We aimed to describe imaging findings in primary inflammatory choriocapillaropathies (PICCPs) after a photobleaching process. METHODS: 2Images from six consecutive cases of patients affected by PICCPs (four with multiple evanescent white dot syndrome and two with multifocal choroiditis) were reviewed. Patients underwent fundus autofluorescence (FAF), fluorescein angiography (FA), indocyanine green angiography (ICGA), and spectral-domain optical coherence tomography (SD-OCT) by means of the Spectralis HRA (Heidelberg Engineering, Heidelberg, Germany). FAF images were acquired at the beginning of the examination in partially dark-adapted conditions followed by light adapted conditions. RESULTS: During the active phase of the diseases, all patients showed areas of increased FAF that became isoautofluorescent after photobleaching. Simultaneously with increased FAF, the ICGA showed typical hypofluorescent dark areas that were more evident in the late phase. SD-OCT showed disruptions in the hyper-reflective band at the ellipsoid zone. CONCLUSIONS:FAF and SD-OCT are complementary imaging techniques that show alterations in the outer retina of patients affected by PICCPs.
Authors: Anthony Joseph; Ehsan Rahimy; K Bailey Freund; John A Sorenson; David Sarraf Journal: Ophthalmic Surg Lasers Imaging Retina Date: 2013-11-01 Impact factor: 1.300
Authors: Svetlana V Jovanovic; Nenad T Petrovic; Maja Lj Zivkovic; Zorica G Toncic; Tatjana S Sarenac Vulovic Journal: Int J Ophthalmol Date: 2017-12-18 Impact factor: 1.779