Ronaldo Campos Hallal1, Juan Carlos Raxach2, Nêmora Tregnago Barcellos3, Ivia Maksud4. 1. Santa Casa de Porto Alegre, Porto Alegre, RS, Brasil. 2. Associação Brasileira Interdisciplinar de AIDS, Rio de Janeiro, RJ, Brasil. 3. Hospital Sanatório Partenon, Universidade do Vale do Rio dos Sinos, Porto Alegre, RS, Brazil. 4. Instituto Fernandes Figueira, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil.
Abstract
INTRODUCTION: The use antiretroviral reduces the sexual transmission of HIV, expanding interventions for serodiscordant couples. OBJECTIVE: This article aims to review the use of antiretroviral and other prevention interventions among serodiscordant couples and to analyze its use in Brazil. METHODS: A retrospective review was performed through the MEDLINE database and bases included in the Biblioteca Virtual em Saúde. RESULTS: The articles recovered exhibit four main strategies: (1) condom; (2) reduction of risks in sexual practices; (3) use of antiretrovirals, particularly early initiation of antiretroviral therapy (TASP) and pre-exposure prophylaxis (PrEP); (4) risk reduction in reproduction. DISCUSSION: TASP is highly effective in reducing sexual transmission, PrEP was tested in serodiscordant couples and both reduce the sexual transmission risk in different sexual practices, enabling individualized prevention strategies. CONCLUSIONS: When used in combination, antiretrovirals and sexual practices with condoms offer greater efficacy than any single strategy. The combined use of new and old strategies allows us to build a prevention policy for all.
INTRODUCTION: The use antiretroviral reduces the sexual transmission of HIV, expanding interventions for serodiscordant couples. OBJECTIVE: This article aims to review the use of antiretroviral and other prevention interventions among serodiscordant couples and to analyze its use in Brazil. METHODS: A retrospective review was performed through the MEDLINE database and bases included in the Biblioteca Virtual em Saúde. RESULTS: The articles recovered exhibit four main strategies: (1) condom; (2) reduction of risks in sexual practices; (3) use of antiretrovirals, particularly early initiation of antiretroviral therapy (TASP) and pre-exposure prophylaxis (PrEP); (4) risk reduction in reproduction. DISCUSSION: TASP is highly effective in reducing sexual transmission, PrEP was tested in serodiscordant couples and both reduce the sexual transmission risk in different sexual practices, enabling individualized prevention strategies. CONCLUSIONS: When used in combination, antiretrovirals and sexual practices with condoms offer greater efficacy than any single strategy. The combined use of new and old strategies allows us to build a prevention policy for all.
Authors: Kiffer G Card; Nathan J Lachowsky; Zishan Cui; Susan Shurgold; Heather L Armstrong; Ashleigh J Rich; Jamie I Forrest; Maya Gislason; David M Moore; Eric A Roth; Robert S Hogg Journal: AIDS Educ Prev Date: 2017-04