Literature DB >> 26629141

Impact of anxiety level on circadian rhythm of blood pressure in hypertensive patients.

Mehmet Emre Özpelit1, Ebru Özpelit2, Nazile Bilgin Doğan3, Nihat Pekel1, Ferhat Ozyurtlu4, Akar Yılmaz1, Serkan Saygı1, İstemihan Tengiz1, Ertugrul Ercan1.   

Abstract

INTRODUCTION: Considering the high prevalence rates and growing incidences of hypertension (HT) and anxiety disorders in the modern world, a full understanding of anxiety's relationship to HT is crucial. In this study we aimed to investigate the effects of anxiety level on circadian rhythm of blood pressure (BP) in hypertensive patients. MATERIAL AND
METHOD: This cross-sectional study included 160 previously diagnosed essential hypertensive patients (80 female, 80 male, mean age: 55.3±15.1 years). All participants underwent 24 h ambulatory blood pressure monitoring (ABPM) and filled State-Trait Anxiety Inventory (STAI) (trait) Questionnaire. The study population was divided into 2 groups according to their STAI scores; an anxiety group (n=97; STAI ≥45) and a control group (n=63; STAI<44). Clinical characteristics, laboratory findings and ABPM measurements were compared between the groups.
RESULTS: There was no significant difference between the groups for ABPM parameters except morning blood pressure surge (MBPS). Anxiety group had a significantly higher MBPS compared to control group (14.4±17.0 vs 9.1±11.9 mmHg, P:0.03). Multivariate analysis showed that duration of HT and STAI score were the only independent predictors of MBPS.
CONCLUSION: Patients' anxiety level is associated with MBPS which is an independent risk factor for cardiovascular complications. Assessment and control of anxiety seems to be worthy in effective treatment of hypertension.

Entities:  

Keywords:  Hypertension; anxiety; morning blood pressure surge

Year:  2015        PMID: 26629141      PMCID: PMC4659029     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


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