Literature DB >> 26628312

An intriguing case of locked jaw secondary to melioidosis.

Tejasvini Vaid1, Karthik Rao1, Handattu Manjunath Hande2.   

Abstract

A 56-year-old woman presented with fever, pain and restriction of movement of the right temporomandibular joint. She was premorbidly diagnosed to have type 2 diabetes mellitus and rheumatoid arthritis. Local examination revealed a poorly demarcated severely tender, erythematous swelling in the right preauricular region. All haematological and biochemical investigations were within normal limits. MRI of the neck revealed the presence of a masticator space infection with intramuscular abscess involving the masseter and the temporalis muscles along with intracranial extension. Osteomyelitic changes were detected in the right mandibular condyle, temporal bone and in the temporomandibular joint. Melioidosis was suspected due to this unique clinical presentation of an abscess at an unusual and atypical site. Blood cultures identified the Gram-negative bacilli Burkholderia pseudomallei, which established the diagnosis of Melioidosis. Remarkable improvement was attained with antibiotics meropenem and cotrimoxazole, deferring the need for any surgical intervention. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26628312      PMCID: PMC4680290          DOI: 10.1136/bcr-2015-213060

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  18 in total

1.  Halving of mortality of severe melioidosis by ceftazidime.

Authors:  N J White; D A Dance; W Chaowagul; Y Wattanagoon; V Wuthiekanun; N Pitakwatchara
Journal:  Lancet       Date:  1989-09-23       Impact factor: 79.321

2.  Oxidative metabolism and phagocytosis of polymorphonuclear leukocytes in patients with chronic renal failure.

Authors:  Y Hirabayashi; T Kobayashi; A Nishikawa; H Okazaki; T Aoki; J Takaya; Y Kobayashi
Journal:  Nephron       Date:  1988       Impact factor: 2.847

Review 3.  Melioidosis: epidemiology, pathophysiology, and management.

Authors:  Allen C Cheng; Bart J Currie
Journal:  Clin Microbiol Rev       Date:  2005-04       Impact factor: 26.132

4.  Comparison of imipenem and ceftazidime as therapy for severe melioidosis.

Authors:  A J Simpson; Y Suputtamongkol; M D Smith; B J Angus; A Rajanuwong; V Wuthiekanun; P A Howe; A L Walsh; W Chaowagul; N J White
Journal:  Clin Infect Dis       Date:  1999-08       Impact factor: 9.079

5.  Cerebral melioidosis in Singapore: a review of five cases.

Authors:  D R Chadwick; B Ang; Y Y Sitoh; C C Lee
Journal:  Trans R Soc Trop Med Hyg       Date:  2002 Jan-Feb       Impact factor: 2.184

6.  Imipenem for the treatment of melioidosis.

Authors:  M A Minassian; A Gage; E Price; A M Sefton
Journal:  Int J Antimicrob Agents       Date:  1999-08       Impact factor: 5.283

7.  Neutrophil bactericidal function in diabetes mellitus: evidence for association with blood glucose control.

Authors:  S J Gallacher; G Thomson; W D Fraser; B M Fisher; C G Gemmell; A C MacCuish
Journal:  Diabet Med       Date:  1995-10       Impact factor: 4.359

8.  The epidemiology and clinical spectrum of melioidosis: 540 cases from the 20 year Darwin prospective study.

Authors:  Bart J Currie; Linda Ward; Allen C Cheng
Journal:  PLoS Negl Trop Dis       Date:  2010-11-30

9.  Outcomes of patients with melioidosis treated with meropenem.

Authors:  Allen C Cheng; Dale A Fisher; Nicholas M Anstey; Dianne P Stephens; Susan P Jacups; Bart J Currie
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

Review 10.  Cerebral melioidosis for the first time in the western hemisphere.

Authors:  Matthew L Vestal; Emily B Wong; Dan A Milner; William B Gormley; Ian F Dunn
Journal:  J Neurosurg       Date:  2013-06-14       Impact factor: 5.115

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