Literature DB >> 26628310

Leucapheresis for management of retinopathy in chronic myeloid leukaemia.

Muhajir Mohamed1, Carmen Oakley2, Fiona McEwen1, Georgina Connelley1.   

Abstract

Chronic myeloid leukaemia is a myeloproliferative neoplasm characterised by granulocytic hyperplasia in the bone marrow and the presence of a specific cytogenetic abnormality known as Philadelphia chromosome with fusion of breakpoint cluster region (BCR) and ableson (ABL) genes. Retinopathy is a rare sight-threatening complication of chronic myeloid leukaemia, which occurs due to leucostasis in retinal blood vessels. We report a case of a patient who presented with visual impairment due to leucostasis, who was successfully managed by leucapheresis along with BCR-ABL tyrosine kinase inhibitor. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID： 26628310      PMCID： PMC4680575          DOI： 10.1136/bcr-2015-212889

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  9 in total

1.  Chronic myelogenous leukemia manifested as bilateral proliferative retinopathy.

Authors:  Naresh Mandava; Deborah Costakos; Heather M Bartlett
Journal:  Arch Ophthalmol       Date:  2005-04

Review 2.  Hyperleukocytosis, leukostasis and leukapheresis: practice management.

Authors:  Chezi Ganzel; Joanne Becker; Paul D Mintz; Hillard M Lazarus; Jacob M Rowe
Journal:  Blood Rev       Date:  2012-02-23       Impact factor: 8.250

Review 3.  Leukocytoreduction for acute leukemia.

Authors:  Pierluigi Porcu; Sherif Farag; Guido Marcucci; Spero R Cataland; Melanie S Kennedy; Michael Bissell
Journal:  Ther Apher       Date:  2002-02

4.  A case report of therapeutic leukapheresis in an adult with chronic myelogenous leukemia presenting with hyperleukocytosis and leukostasis.

Authors:  Shahzad Shafique; Robert Bona; Andre A Kaplan
Journal:  Ther Apher Dial       Date:  2007-04       Impact factor: 1.762

5.  Peripheral retinal nonperfusion associated with chronic myeloid leukemia.

Authors:  Siamak Nobacht; Kathleen F K Vandoninck; August F Deutman; B Jeroen Klevering
Journal:  Am J Ophthalmol       Date:  2003-03       Impact factor: 5.258

Review 6.  Therapeutic apheresis in hyperleukocytosis and hyperviscosity syndrome.

Authors:  William Blum; Pierluigi Porcu
Journal:  Semin Thromb Hemost       Date:  2007-06       Impact factor: 4.180

Review 7.  Expression of angiogenic factors in chronic myeloid leukaemia: role of the bcr/abl oncogene, biochemical mechanisms, and potential clinical implications.

Authors:  C Sillaber; M Mayerhofer; K J Aichberger; M-T Krauth; P Valent
Journal:  Eur J Clin Invest       Date:  2004-08       Impact factor: 4.686

8.  Visual Disturbance as the first Symptom of Chronic Myeloid Leukemia.

Authors:  Philemon K Huang; Srinivasan Sanjay
Journal:  Middle East Afr J Ophthalmol       Date:  2011-10

9.  Bilateral proliferative retinopathy as the initial presentation of chronic myeloid leukemia.

Authors:  Mafalda S F Macedo; Ana R M Figueiredo; Natália N Ferreira; Irene M A Barbosa; Maria João F B S Furtado; Nuno F C B A Correia; Miguel P Gomes; Miguel R B Lume; Maria João S Menéres; Marinho M N Santos; M Angelina C S Meireles
Journal:  Middle East Afr J Ophthalmol       Date:  2013 Oct-Dec
  9 in total
  1 in total

Review 1.  Leukostasis retinopathy: An uncommon visual threatening complication of chronic myeloid leukemia with severe hyperleukocytosis - A case report and review of the literature.

Authors:  Bo Chen; Xiaoqin Yan; Xian Zhang; Hong Yang
Journal:  Indian J Ophthalmol       Date:  2018-12       Impact factor: 1.848
  1 in total

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